Improving the Efficiency of Single-Isocenter Multiple Metastases Stereotactic Radiosurgery Treatment.

Multiple brain metastases can be treated efficiently with stereotactic radiosurgery (SRS) using a single-isocenter dynamic conformal arc (SIDCA) technique. Currently, plans are manually optimized, which may lead to unnecessary table angles and arcs being used. This study aimed to evaluate an automatic 4π optimization SIDCA algorithm for treatment efficiency and plan quality. Automatic 4π-optimized SIDCA plans were created and compared with the manually optimized clinical plans for 54 patients who underwent single-fraction SRS for 2 to 10 metastases. The number of table angles and number of arcs were compared with a paired The automatic plans significantly improved treatment efficiency with a mean reduction in the number of table angles and arcs of -0.5 ± 0.1 and -1.3 ± 0.2, respectively (±SE; both Automatic 4π optimization can generate SIDCA SRS plans with improved treatment efficiency and noninferior plan quality.

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