Sexual dysfunction among people with mental illness in Africa: A systematic review and meta-analysis study.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2024
Historique:
received: 02 05 2024
accepted: 18 07 2024
medline: 31 7 2024
pubmed: 31 7 2024
entrez: 31 7 2024
Statut: epublish

Résumé

Sexual dysfunction is the most frequent health problem among psychiatric patients. This could be the result of both the nature of the illness itself and the side effects of prescribed psychotropic medications. It also significantly affects an individual's general well-being, interpersonal relationships, self-esteem, and treatment outcomes. Therefore, the current systematic review and meta-analysis was conducted to determine the combined prevalence of sexual dysfunction and its correlated factors among people with mental illness. We retrieved eligible primary studies using various search databases like PubMed, EMBASE, Science Direct, African Journal Online, Google Scholar, and Psychiatry Online. The report of this systematic review was reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We used standardized data extraction checklists and STATA version 14 for data extraction and analysis, respectively. The I-squared statistics test was used to check statistical heterogeneity within the included articles. Publication bias was assessed using a funnel plot and the Egger test. To estimate the overall prevalence and correlated factors of sexual dysfunction, a random effects model meta-analysis was employed. In this meta-analysis, a total of 15 primary studies with 2849 psychiatric patients were included. The overall pooled prevalence of sexual dysfunction among psychiatric patients in Africa was 58.42% (95% CI: 49.55, 67.28). Having older age (OR = 1.92, 95% CI: 1.28, 2.87), longer duration of illness (OR = 2.60, 95% CI: 1.14, 5.93), history of relapse (OR = 3.51, 95% CI: 1.47, 8.43), poor quality of life (OR = 3.89, 95% CI: 2.15, 7.05), and antipsychotic medications (OR = 2.99, 95% CI: 1.84, 4.86) were significantly associated with sexual dysfunction. This meta-analysis revealed that approximately two-thirds of psychiatric patients in Africa are affected by sexual dysfunction. Therefore, the findings of this study recommend that when evaluating psychiatric patients, health professionals should focus more on sexual dysfunction. It is also essential to promote awareness and incorporate sexual health assessment and intervention into mental health services to reduce the overall burden of the problem.

Sections du résumé

BACKGROUND BACKGROUND
Sexual dysfunction is the most frequent health problem among psychiatric patients. This could be the result of both the nature of the illness itself and the side effects of prescribed psychotropic medications. It also significantly affects an individual's general well-being, interpersonal relationships, self-esteem, and treatment outcomes. Therefore, the current systematic review and meta-analysis was conducted to determine the combined prevalence of sexual dysfunction and its correlated factors among people with mental illness.
METHODS METHODS
We retrieved eligible primary studies using various search databases like PubMed, EMBASE, Science Direct, African Journal Online, Google Scholar, and Psychiatry Online. The report of this systematic review was reported following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines. We used standardized data extraction checklists and STATA version 14 for data extraction and analysis, respectively. The I-squared statistics test was used to check statistical heterogeneity within the included articles. Publication bias was assessed using a funnel plot and the Egger test. To estimate the overall prevalence and correlated factors of sexual dysfunction, a random effects model meta-analysis was employed.
RESULTS RESULTS
In this meta-analysis, a total of 15 primary studies with 2849 psychiatric patients were included. The overall pooled prevalence of sexual dysfunction among psychiatric patients in Africa was 58.42% (95% CI: 49.55, 67.28). Having older age (OR = 1.92, 95% CI: 1.28, 2.87), longer duration of illness (OR = 2.60, 95% CI: 1.14, 5.93), history of relapse (OR = 3.51, 95% CI: 1.47, 8.43), poor quality of life (OR = 3.89, 95% CI: 2.15, 7.05), and antipsychotic medications (OR = 2.99, 95% CI: 1.84, 4.86) were significantly associated with sexual dysfunction.
CONCLUSION CONCLUSIONS
This meta-analysis revealed that approximately two-thirds of psychiatric patients in Africa are affected by sexual dysfunction. Therefore, the findings of this study recommend that when evaluating psychiatric patients, health professionals should focus more on sexual dysfunction. It is also essential to promote awareness and incorporate sexual health assessment and intervention into mental health services to reduce the overall burden of the problem.

Identifiants

pubmed: 39083558
doi: 10.1371/journal.pone.0308272
pii: PONE-D-24-17632
doi:

Types de publication

Journal Article Systematic Review Meta-Analysis

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0308272

Informations de copyright

Copyright: © 2024 Fentahun et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors declare that they have no competing interests.

Auteurs

Setegn Fentahun (S)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Mamaru Melkam (M)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Gebresilassie Tadesse (G)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Gidey Rtbey (G)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Fantahun Andualem (F)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Yilkal Abebaw Wassie (YA)

Department of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Gebremariam Wulie Geremew (GW)

Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Tekletsadik Tekleslassie Alemayehu (TT)

Department of Social and Administrative Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Tewodros Denekew Haile (TD)

University of Gondar, College of Medicine and Health Science, School of Pharmacy, Department of Pharmaceutical Chemistry.

Tilahun Nega Godana (TN)

Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar Ethiopia.

Berihun Agegn Mengistie (BA)

Department of General Midwifery, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Mulualem Kelebie (M)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Girum Nakie (G)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Techilo Tinsae (T)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Girmaw Medfu Takelle (GM)

Department of Psychiatry, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

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