[A Case Report of Successful Treatment with Dose-controlled mFOFOX6+Bevacizumab for Metastatic Colorectal Cancer in Patient Receiving Hemodialysis].
Humans
Bevacizumab
/ administration & dosage
Male
Aged
Renal Dialysis
Antineoplastic Combined Chemotherapy Protocols
/ administration & dosage
Liver Neoplasms
/ secondary
Organoplatinum Compounds
/ administration & dosage
Fluorouracil
/ administration & dosage
Leucovorin
/ administration & dosage
Treatment Outcome
Colectomy
Colorectal Neoplasms
/ pathology
Hepatectomy
Laparoscopy
chemotherapy
colorectal caner
hemodialysis
Journal
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
ISSN: 1347-5231
Titre abrégé: Yakugaku Zasshi
Pays: Japan
ID NLM: 0413613
Informations de publication
Date de publication:
2024
2024
Historique:
medline:
1
8
2024
pubmed:
1
8
2024
entrez:
31
7
2024
Statut:
ppublish
Résumé
A 65-years-old man undergoing hemodialysis for chronic kidney disease was diagnosed with ascending colon cancer and 3 hepatic metastases. He was administered mFOLFOX6 (reducing the dose to 50%) plus bevacizumab (BEV) therapy. Hemodialysis was performed 4 h after administration of oxaliplatin on day1 and repeated three times a week. No serious adverse events were observed. After 4 courses of chemotherapy, a computer tomography scan showed that the hepatic metastases had reduced. 2 courses of mFOLFOX6 (increasing the dose to 75%) plus BEV therapy were added, he was operated by laparoscopic right hemicolectomy and laparoscopic patrial hepatectomy. He has been in remission for 2 years and 4 months since the surgery. Dose-adjusted chemotherapy with hemodialysis was effective and improve the prognosis of the patient.
Identifiants
pubmed: 39085061
doi: 10.1248/yakushi.24-00004
doi:
Substances chimiques
Bevacizumab
2S9ZZM9Q9V
Organoplatinum Compounds
0
Fluorouracil
U3P01618RT
Leucovorin
Q573I9DVLP
Types de publication
Case Reports
Journal Article
English Abstract
Langues
jpn
Sous-ensembles de citation
IM