Young-Onset Rectal Cancer: Is It for Real?

Humans Rectal Neoplasms / pathology Age of Onset Risk Factors Neoplasm Staging Incidence Prognosis
Colorectal cancer Early-onset colorectal cancer Hereditary colorectal cancer Rectal cancer Young adults

Journal

Advances in surgery
ISSN: 1878-0555
Titre abrégé: Adv Surg
Pays: United States
ID NLM: 0045335

Informations de publication

Date de publication:
Sep 2024
Historique:
medline: 2 8 2024
pubmed: 2 8 2024
entrez: 1 8 2024
Statut: ppublish

Résumé

The incidence of early-onset colorectal cancer has been rising over the last two decades. Tumors in young patients have distinct features compared to older patients. They predominantly arise in the distal colon and rectum and have poor histological features. Patients tend to present at a more advanced stage and be exposed to more aggressive management approaches; however, this has not translated into a significant survival benefit compared to their older counterparts. This chapter will share current evidence on risk factors and management options for early onset colorectal cancer with a focus on rectal cancer.

Identifiants

DOI: 10.1016/j.yasu.2024.04.015 PMID: 39089782
pubmed: 39089782
pii: S0065-3411(24)00015-0
doi: 10.1016/j.yasu.2024.04.015
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

275-291

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Disclosure The authors have nothing to disclose.

Auteurs

Reena S Suresh (RS)

Department of Surgery, Division of Colorectal Surgery, Johns Hopkins School of Medicine, 600 N. Wolfe Street / Blalock 618, Baltimore, MD 21287, USA.

Leonardo E Garcia (LE)

Department of Surgery, Division of Colorectal Surgery, Johns Hopkins School of Medicine, 600 N. Wolfe Street / Blalock 618, Baltimore, MD 21287, USA.

Susan L Gearhart (SL)

Department of Surgery, Division of Colorectal Surgery, Johns Hopkins School of Medicine, 600 N. Wolfe Street / Blalock 618, Baltimore, MD 21287, USA. Electronic address: sdemees1@jhmi.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Young-Onset Rectal Cancer: Is It for Real?
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du rectum › Tumeurs colorectales › Tumeurs du rectum › Young-Onset Rectal Cancer: Is It for Real?
questionsmedicales.fr › Environnement et santé publique › Santé publique › Facteurs épidémiologiques › Facteurs âges › Âge de début › Young-Onset Rectal Cancer: Is It for Real?
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › Young-Onset Rectal Cancer: Is It for Real?
questionsmedicales.fr › Diagnostic › Pronostic › Stadification tumorale › Young-Onset Rectal Cancer: Is It for Real?
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Incidence › Young-Onset Rectal Cancer: Is It for Real?
questionsmedicales.fr › Diagnostic › Pronostic › Young-Onset Rectal Cancer: Is It for Real?