Quantitative Morphological Study of Larynx APUD-Cells in Asphyxial Type of Drowning in Fresh Water (Experimental Study).

APUD-cells asphyxial type of drowning morphometry mucous membrane of the larynx rats

Journal

Bulletin of experimental biology and medicine

ISSN: 1573-8221

Titre abrégé: Bull Exp Biol Med

Pays: United States

ID NLM: 0372557

Informations de publication

Date de publication:
01 Aug 2024

Historique:

received: 21 12 2023

medline: 2 8 2024

pubmed: 2 8 2024

entrez: 1 8 2024

Statut: aheadofprint

Résumé

An additional microscopic diagnostic sign has been identified for verification of asphyxial type of drowning. In white non-linear male rats (age 2 months) subjected to free drowning, significant hyperplasia of argyrophilic and morphofunctional activity of serotonin-containing APUD-cells of the laryngeal mucosa were revealed under conditions of acute anoxia in comparison with the intact control. These changes promote the development of laryngospasm, which prevents water penetration into the airways and lungs in asphyxial type of drowning. The presence of statistically significant hyperplasia of argyrophilic and morphofunctional activity of serotonin-containing APUD-cells of the laryngeal mucosa under conditions of acute anoxia can be used as an additional diagnostic criterion for asphyxial type of drowning in experimental studies.

Identifiants

DOI: 10.1007/s10517-024-06173-1 PMID: 39090466

pubmed: 39090466

doi: 10.1007/s10517-024-06173-1

pii: 10.1007/s10517-024-06173-1

doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

Informations de copyright

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