LYMPH-Q translation, cultural adaptation and validation in Italian language: A prospective PROMs-based study on breast cancer-related arm lymphedema for patients' education.

Breast cancer LYMPH-Q Lymphedema Upper Extremity Lymphedema

Journal

Journal of plastic, reconstructive & aesthetic surgery : JPRAS
ISSN: 1878-0539
Titre abrégé: J Plast Reconstr Aesthet Surg
Pays: Netherlands
ID NLM: 101264239

Informations de publication

Date de publication:
15 Jul 2024
Historique:
received: 20 05 2024
revised: 18 06 2024
accepted: 08 07 2024
medline: 4 8 2024
pubmed: 4 8 2024
entrez: 3 8 2024
Statut: aheadofprint

Résumé

Upper Extremity Lymphedema following oncological breast surgery affects not only the patient's physique, but also the patient's psychological sphere. One of the best known PROMs-based questionnaires for investigating the condition is the LYMPH-Q. The study aimed to perform the Italian translation and cultural adaptation of the LYMPH-Q and to assess if, independently from disease evolution, arm sleeve improves QoL in these patients. Translation included 4 steps: Forward translation, Back translation, Back translation review and Patient interviews. The questionnaire was administered to 50 female patients older than 18 years of age with UEL who received a prescription for daily use of a compression sheath. A second administration took place 30 days after. Forty-four patients completed the study (Group 1: 26 patients with indication to use compression sleeve who wore it; Group 2:18 patients who despite the prescription did not want to wear it. A descriptive statistical analysis was performed with Prism 9 software. T-tests showed statistical significance for changes in "Symptoms," "Function," "Appearance" and "Psychological" scales. There were no statistically significant changes for "Information scale" in Group 1 and for all scales in Group 2. Data from this observational study show that HR-QOL analyzed from the patients' perspective also tends to improve in terms of symptoms, function, appearance, and psychological sphere in patients with BCRL when using a compression sheath. The Lymph-Q has proven to be a valuable ally of the physician attempting to improve treatment approaches for BCRL based not only on scientific evidence but also on PROMs.

Sections du résumé

BACKGROUND BACKGROUND
Upper Extremity Lymphedema following oncological breast surgery affects not only the patient's physique, but also the patient's psychological sphere. One of the best known PROMs-based questionnaires for investigating the condition is the LYMPH-Q. The study aimed to perform the Italian translation and cultural adaptation of the LYMPH-Q and to assess if, independently from disease evolution, arm sleeve improves QoL in these patients.
MATERIALS AND METHODS METHODS
Translation included 4 steps: Forward translation, Back translation, Back translation review and Patient interviews. The questionnaire was administered to 50 female patients older than 18 years of age with UEL who received a prescription for daily use of a compression sheath. A second administration took place 30 days after. Forty-four patients completed the study (Group 1: 26 patients with indication to use compression sleeve who wore it; Group 2:18 patients who despite the prescription did not want to wear it. A descriptive statistical analysis was performed with Prism 9 software.
RESULTS RESULTS
T-tests showed statistical significance for changes in "Symptoms," "Function," "Appearance" and "Psychological" scales. There were no statistically significant changes for "Information scale" in Group 1 and for all scales in Group 2.
CONCLUSION CONCLUSIONS
Data from this observational study show that HR-QOL analyzed from the patients' perspective also tends to improve in terms of symptoms, function, appearance, and psychological sphere in patients with BCRL when using a compression sheath. The Lymph-Q has proven to be a valuable ally of the physician attempting to improve treatment approaches for BCRL based not only on scientific evidence but also on PROMs.

Identifiants

DOI: 10.1016/j.bjps.2024.07.011 PMID: 39096736
pubmed: 39096736
pii: S1748-6815(24)00387-5
doi: 10.1016/j.bjps.2024.07.011
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

199-206

Informations de copyright

Copyright © 2024 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Auteurs

Annalisa Cogliandro (A)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Carlo Mirra (C)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Marco Gratteri (M)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy. Electronic address: m.gratteri@unicampus.it.

Viviana Mannella (V)

Plastic Surgery Unit, Sapienza University of Rome, Rome, Italy.

Rosa Salzillo (R)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Federica Bressi (F)

Physical and Rehabilitative Medicine Department, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Sandra Miccinilli (S)

Physical and Rehabilitative Medicine Department, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Riccardo De Bernardis (R)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Luca Savani (L)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Giovanni Francesco Marangi (GF)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Paolo Persichetti (P)

Department of Plastic, Reconstructive and Cosmetic Surgery, Rome Biomedical Campus Foundation, Via Alvaro del Portillo 200, Rome, Italy.

Classifications MeSH