The phosphatase RosC from Streptomyces davaonensis is used for roseoflavin biosynthesis and has evolved to largely prevent dephosphorylation of the important cofactor riboflavin-5'-phosphate.

Streptomyces davaonensis antibiotics phosphatases riboflavin roseoflavin

Journal

Journal of molecular biology
ISSN: 1089-8638
Titre abrégé: J Mol Biol
Pays: Netherlands
ID NLM: 2985088R

Informations de publication

Date de publication:
01 Aug 2024
Historique:
received: 10 06 2024
revised: 26 07 2024
accepted: 29 07 2024
medline: 4 8 2024
pubmed: 4 8 2024
entrez: 3 8 2024
Statut: aheadofprint

Résumé

The antibiotic roseoflavin is a riboflavin (vitamin B

Identifiants

pubmed: 39097184
pii: S0022-2836(24)00343-7
doi: 10.1016/j.jmb.2024.168734
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

168734

Informations de copyright

Copyright © 2024. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Tanya Joshi (T)

Institute for Technical Microbiology, Department of Biotechnology, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.

Ulrike Demmer (U)

Max-Planck-Institute for Biophysics, Max-von-Laue-Strasse 3, 60438 Frankfurt am Main, Germany.

Carmen Schneider (C)

Institute for Technical Microbiology, Department of Biotechnology, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.

Theresa Glaser (T)

Institute for Technical Microbiology, Department of Biotechnology, Mannheim University of Applied Sciences, 68163 Mannheim, Germany.

Eberhard Warkentin (E)

Max-Planck-Institute for Biophysics, Max-von-Laue-Strasse 3, 60438 Frankfurt am Main, Germany.

Ulrich Ermler (U)

Max-Planck-Institute for Biophysics, Max-von-Laue-Strasse 3, 60438 Frankfurt am Main, Germany.

Matthias Mack (M)

Institute for Technical Microbiology, Department of Biotechnology, Mannheim University of Applied Sciences, 68163 Mannheim, Germany. Electronic address: m.mack@hs-mannheim.de.

Classifications MeSH