Epistatic interaction has the reverse effects with its constitutive quantitative trait loci.

Quantitative Trait Loci Epistasis, Genetic Oryza / genetics Phenotype Models, Genetic
Epistatic interaction Quantitative trait locus Reverse effect Single segment substitution line

Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
06 Aug 2024
Historique:
received: 07 02 2024
accepted: 01 08 2024
medline: 7 8 2024
pubmed: 7 8 2024
entrez: 6 8 2024
Statut: epublish

Résumé

Epistasis is one of important genetic components for a quantitative trait in plant. Eshed and Zamir found negative epistatic interactions of quantitative trait loci in Tomato first. We detected that positive (negative) QTLs generated mostly negative (positive) epistatic interactions on heading date in rice, and then proposed the hypothese that QTL epistasis plays a role of homeostasis in one of our recent papers. In order to further provide additional evidence, the effects of QTLs and their epistatic effects on two quantitative traits of plant height (ph) and thousand kernel weight (tkw) were analyzed in this study. The same regularity was verified again. We detected that positive ph QTLs and negative tkw QTLs always generated reverse epistatic effects, respectively. Moreover, high-order epistatic effects were estimated on these two traits. The sum of all epistatic effects would partially neutralize the additive of constitutive QTL effects. This feature of epistsis would be the mechanism for bionts to maintain homeostasis while the obstacle for human to achieve the pyramiding breeding objectives. More evidences are still being collected to support our assumption.

Identifiants

DOI: 10.1038/s41598-024-69236-3 PMID: 39107519
pubmed: 39107519
doi: 10.1038/s41598-024-69236-3
pii: 10.1038/s41598-024-69236-3
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

18169

Subventions

Organisme : STI 2030-Major Project
ID : 2023ZD04069
Organisme : Guangdong laboratory of Lingnan Modern agriculture of major scientific and technological research projects
ID : NT2021001

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Yuanyuan Liu (Y)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Bihuang Zhu (B)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Jichun Tang (J)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.
Kunpeng Institute of Modern Agriculture at Foshan, Foshan, 528200, People's Republic of China.

Lilong Huang (L)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Guodong Chen (G)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Leyi Chen (L)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Suhong Bu (S)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Haitao Zhu (H)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Zupei Liu (Z)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Zhan Li (Z)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China.

Lijun Meng (L)

Kunpeng Institute of Modern Agriculture at Foshan, Foshan, 528200, People's Republic of China. menglijun@caas.cn.

Guifu Liu (G)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China. guifuliu@scau.edu.cn.

Shaokui Wang (S)

Guangdong Key Laboratory of Plant Molecular Breeding, South China Agricultural University, Guangzhou, 510642, People's Republic of China. shaokuiwang@scau.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Génome › Composants de génome › Locus génétiques › Locus de caractère quantitatif › Epistatic interaction has the reverse effects...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Épistasie › Epistatic interaction has the reverse effects...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Poaceae › Oryza › Epistatic interaction has the reverse effects...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › Epistatic interaction has the reverse effects...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles génétiques › Epistatic interaction has the reverse effects...