Hip resurfacing versus total hip arthroplasty: a systematic review and meta-analysis of randomized clinical trials.

Complications Functional outcomes Hip resurfacing Implant survivorship Meta-analysis Total hip arthroplasty

Journal

International orthopaedics
ISSN: 1432-5195
Titre abrégé: Int Orthop
Pays: Germany
ID NLM: 7705431

Informations de publication

Date de publication:
07 Aug 2024
Historique:
received: 19 06 2024
accepted: 29 07 2024
medline: 7 8 2024
pubmed: 7 8 2024
entrez: 6 8 2024
Statut: aheadofprint

Résumé

Total hip arthroplasty (THA) is the gold standard in the treatment of advanced hip osteoarthritis. However, hip resurfacing (HR) arthroplasty may present a viable alternative. The aim of this study was to compare complications, implant survivorship, and functional outcomes between HR and THA, to assess HR as a valid and safe alternative to THA. Inclusion criteria were randomized clinical trials (RCTs) published in English, comparing clinical outcomes and complications between HR and THA. A systematic review of the literature was performed on PubMed, Scopus and Cochrane Library, following the PRISMA 2020 statement, from January 1, 2015 to November 30, 2023. A meta-analysis was performed by Review Manager (RevMan) software version 5.4 to compare the rates of revisions, dislocations, infection, aseptic loosening and pseudotumor, and the clinical outcomes between the two groups. We used the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) to assess the risk of bias. A total of 8 RCT were included, involving 844 patients (387 hips for HR group and 469 hips for THA group). The mean follow-up was 7.72 years. There were no statistically significant differences between the two groups for UCLA and WOMAC score, revision rate, infection, aseptic loosening and pseudotumor (all p > 0.05), while the dislocation rate was significantly lower in the HR group (p = 0.04). HR is a safe and effective alternative to THA. However, several factors are involved to reduce the complication rate and achieve high implant survival.

Identifiants

pubmed: 39107628
doi: 10.1007/s00264-024-06269-3
pii: 10.1007/s00264-024-06269-3
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s) under exclusive licence to SICOT aisbl.

Références

Learmonth ID, Young C, Rorabeck C (2007) The operation of the century: total hip replacement. Lancet 370:1508–1519. https://doi.org/10.1016/S0140-6736(07)60457-7
doi: 10.1016/S0140-6736(07)60457-7 pubmed: 17964352
Kim Y-H, Park J-W, Jang Y-S, Kim E-J (2023) Long-term results (Minimum of 20 years) of a pure proximal-loading metaphyseal-fitting anatomic cementless stem without distal stem fixation in hip arthroplasty. J Arthroplast 38:743–750. https://doi.org/10.1016/j.arth.2022.10.034
doi: 10.1016/j.arth.2022.10.034
Xu J, Oni T, Shen D et al (2022) Long-term results of Alumina Ceramic-On-Ceramic Bearings in Cementless Total Hip Arthroplasty: a 20-Year Minimum Follow-Up. J Arthroplast 37:549–553. https://doi.org/10.1016/j.arth.2021.11.028
doi: 10.1016/j.arth.2021.11.028
Ateschrang A, Weise K, Weller S et al (2014) Long-term results using the straight tapered femoral cementless hip stem in total hip arthroplasty: a Minimum of twenty-year Follow-Up. J Arthroplast 29:1559–1565. https://doi.org/10.1016/j.arth.2014.02.015
doi: 10.1016/j.arth.2014.02.015
Falez F, Papalia M, Favetti F et al (2017) Total hip arthroplasty instability in Italy. Int Orthop (SICOT) 41:635–644. https://doi.org/10.1007/s00264-016-3345-6
doi: 10.1007/s00264-016-3345-6
Annals of the Royal College of Surgeons of England (1983) vol. 65
Falez F, Favetti F, Casella F, Panegrossi G (2008) Hip resurfacing: why does it fail? Early results and critical analysis of our first 60 cases. Int Orthop (SICO 32:209–216. https://doi.org/10.1007/s00264-006-0313-6
doi: 10.1007/s00264-006-0313-6
McMinn D, Treacy R, Lin K, Pynsent P (1996) Metal on metal surface replacement of the hip: experience of the McMinn Prosthesis. Clin Orthop Relat Res 329:S89–S98. https://doi.org/10.1097/00003086-199608001-00009
doi: 10.1097/00003086-199608001-00009
McMinn DJW (2009) Modern hip resurfacing. Springer London, London
doi: 10.1007/978-1-84800-088-9
Haddad FS, Thakrar RR, Hart AJ et al (2011) Metal-on-metal bearings: THE EVIDENCE SO FAR. The Journal of bone and joint surgery British volume. 93–B:572–579. https://doi.org/10.1302/0301-620X.93B4.26429
Trentani C, Vaccarino F (1978) The Paltrinieri-Trentani Hip Joint Resurface Arthroplasty. Clin Orthop Relat Res NA:36–40. https://doi.org/10.1097/00003086-197807000-00006
doi: 10.1097/00003086-197807000-00006
Gerard Y (1978) Hip Arthroplasty By Matching Cups: Clinical Orthopaedics and Related Research NA;25???35. https://doi.org/10.1097/00003086-197807000-00005
Charnley J, ARTHROPLASTY OF THE HIP A New Operation (1961) Lancet 277:1129–1132. https://doi.org/10.1016/S0140-6736(61)92063-3
doi: 10.1016/S0140-6736(61)92063-3
Van Gerwen M, Shaerf DA, Veen RM (2010) Hip resurfacing arthroplasty: a systematic review of functional outcome. Acta Orthop 81:680–683. https://doi.org/10.3109/17453674.2010.501742
doi: 10.3109/17453674.2010.501742 pubmed: 20860440 pmcid: 3216077
Van Der Straeten C, Gross TP, Amstutz H et al (2022) Hip resurfacing arthroplasty in young patients: international high-volume centres’ report on the outcome of 11,382 metal-on-metal hip resurfacing arthroplasties in patients ⩽50 years at surgery. HIP Int 32:353–362. https://doi.org/10.1177/1120700020957354
doi: 10.1177/1120700020957354 pubmed: 32905713
Al-Jabri T, Ridha M, McCulloch RA et al (2023) Hip resurfacing arthroplasty: past, Present and Future. Orthop Rev 15. https://doi.org/10.52965/001c.77745
Maillot C, Auvinet E, Harman C et al (2020) Hip resurfacing generates a more physiological gait than total hip replacement: a case-control study. Orthop Traumatology: Surg Res 106:527–534. https://doi.org/10.1016/j.otsr.2019.12.020
doi: 10.1016/j.otsr.2019.12.020
Loughead JM, Chesney D, Holland JP, McCaskie AW (2005) Comparison of offset in Birmingham hip resurfacing and hybrid total hip arthroplasty. J Bone Joint Surg Br Volume 87–B:163–166. https://doi.org/10.1302/0301-620X.87B2.15151
doi: 10.1302/0301-620X.87B2.15151
Kishida Y, Sugano N, Nishii T et al (2004) Preservation of the bone mineral density of the femur after surface replacement of the hip. J Bone Joint Surg Br Volume 86–B:185–189. https://doi.org/10.1302/0301-620X.86B2.14338
doi: 10.1302/0301-620X.86B2.14338
Sershon R, Balkissoon R, Valle CJD (2016) Current indications for hip resurfacing arthroplasty in 2016. Curr Rev Musculoskelet Med 9:84–92. https://doi.org/10.1007/s12178-016-9324-0
doi: 10.1007/s12178-016-9324-0 pubmed: 26830851 pmcid: 4762803
McMinn DJW, Daniel J, Ziaee H, Pradhan C (2011) Indications and results of hip resurfacing. Int Orthop (SICOT) 35:231–237. https://doi.org/10.1007/s00264-010-1148-8
doi: 10.1007/s00264-010-1148-8
Gerhardt DMJM, Smolders JMH, Rijnders TAJM et al (2015) Changes in bone Mineral density and femoral Neck narrowing in the proximal Femur three to five years after hip resurfacing Versus Conventional Total Hip Arthroplasty. J Arthroplast 30:308–314. https://doi.org/10.1016/j.arth.2014.09.007
doi: 10.1016/j.arth.2014.09.007
Marshall DA, Pykerman K, Werle J et al (2014) Hip resurfacing versus total hip arthroplasty: a systematic review comparing standardized outcomes. Clin Orthop Relat Res 472:2217–2230. https://doi.org/10.1007/s11999-014-3556-3
doi: 10.1007/s11999-014-3556-3 pubmed: 24700446 pmcid: 4048407
Fouilleron N, Wavreille G, Endjah N, Girard J (2012) Running activity after hip resurfacing arthroplasty: a prospective study. Am J Sports Med 40:889–894. https://doi.org/10.1177/0363546511434564
doi: 10.1177/0363546511434564 pubmed: 22302205
Andy Murray Former British number one has resurfacing surgery on hip. BBC Sport. https://www.bbc.co.uk/sport/tennis/46916064 (date last accessed 15 February 2023).
Marker DR, Strimbu K, McGrath MS et al (2009) Resurfacing versus conventional total hip arthroplasty - review of comparative clinical and basic science studies. Bull NYU Hosp Jt Dis 67:120–127
pubmed: 19583538
Calkins TE, Suleiman LI, Culvern C et al (2021) Hip resurfacing arthroplasty and total hip arthroplasty in the same patient: which do they prefer? HIP Int 31:328–334. https://doi.org/10.1177/1120700019882922
doi: 10.1177/1120700019882922 pubmed: 31615288
Falez F, Casella F, Papalia M (2015) Current concepts, classification, and results in short stem hip arthroplasty. https://doi.org/10.3928/01477447-20150215-50 . Orthopedics 38:
Amstutz HC, Beaulé PE, Dorey FJ et al (2006) Metal-on-metal hybrid surface arthroplasty: Surgical technique. J Bone Joint Surg 88:234–249. https://doi.org/10.2106/JBJS.F.00273
doi: 10.2106/JBJS.F.00273 pubmed: 16951096
Girard J, Lavigne M, Vendittoli P-A, Roy AG, RANDOMISED STUDY COMPARING TOTAL HIP RESURFACING AND TOTAL HIP ARTHROPLASTY (2006) Biomechanical reconstruction of the hip: a. J Bone Joint Surg Br Volume 88–B:721–726. https://doi.org/10.1302/0301-620X.88B6.17447
doi: 10.1302/0301-620X.88B6.17447
Amstutz HC, Le Duff MJ (2018) The mean ten-year results of metal-on-metal hybrid hip resurfacing arthroplasty. Bone Joint J 100–B:1424–1433. https://doi.org/10.1302/0301-620X.100B11.BJJ-2017-1459.R2
doi: 10.1302/0301-620X.100B11.BJJ-2017-1459.R2 pubmed: 30418058
Shimmin AJ, Bare J, Back DL (2005) Complications Associated with Hip Resurfacing Arthroplasty. Orthop Clin North Am 36:187–193. https://doi.org/10.1016/j.ocl.2005.01.002
doi: 10.1016/j.ocl.2005.01.002 pubmed: 15833456
Matharu GS, Berryman F, Judge A et al (2017) Blood metal Ion Thresholds to identify patients with metal-on-metal hip implants at risk of adverse reactions to metal debris: an external Multicenter Validation Study of Birmingham Hip Resurfacing and Corail-Pinnacle implants. J Bone Joint Surg 99:1532–1539. https://doi.org/10.2106/JBJS.16.01568
doi: 10.2106/JBJS.16.01568 pubmed: 28926382
Granchi D, Savarino LM, Ciapetti G, Baldini N (2018) Biological effects of metal degradation in hip arthroplasties. Crit Rev Toxicol 48:170–193. https://doi.org/10.1080/10408444.2017.1392927
doi: 10.1080/10408444.2017.1392927 pubmed: 29130357
Hastie GR, Collinson SC, Aqil A et al (2021) Study to assess the rate of adverse reaction to metal debris in hip resurfacing at a minimum 13-year follow-up. J Arthroplast 36:1055–1059. https://doi.org/10.1016/j.arth.2020.09.056
doi: 10.1016/j.arth.2020.09.056
Matharu GS, Pandit HG, Murray DW, Judge A (2016) Adverse reactions to metal debris occur with all types of hip replacement not just metal-on-metal hips: a retrospective observational study of 3340 revisions for adverse reactions to metal debris from the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man. BMC Musculoskelet Disord 17:495. https://doi.org/10.1186/s12891-016-1329-8
doi: 10.1186/s12891-016-1329-8 pubmed: 27955657 pmcid: 5153685
Kumar P, Ksheersagar V, Aggarwal S et al (2022) Complications and mid to long term outcomes for hip resurfacing versus total hip replacement: a systematic review and meta-analysis. Eur J Orthop Surg Traumatol 33:1495–1504. https://doi.org/10.1007/s00590-022-03361-5
doi: 10.1007/s00590-022-03361-5 pubmed: 36006506
Hellman MD, Ford MC, Barrack RL (2019) Is there evidence to support an indication for surface replacement arthroplasty? A systematic review. Bone Joint J 101–B:32–40. https://doi.org/10.1302/0301-620X.101B1.BJJ-2018-0508.R1
doi: 10.1302/0301-620X.101B1.BJJ-2018-0508.R1 pubmed: 30648490
Palazzuolo M, Bensa A, Bauer S et al (2023) Resurfacing hip arthroplasty is a safe and effective alternative to total hip arthroplasty in Young patients: a systematic review and Meta-analysis. https://doi.org/10.3390/jcm12062093 . JCM 12:2093
Bisseling P, Smolders JMH, Hol A, Van Susante JLC (2015) Metal ion levels and functional results following resurfacing hip arthroplasty Versus Conventional Small-Diameter Metal-on-metal total hip arthroplasty; a 3 to 5year Follow-Up of a Randomized Controlled Trial. J Arthroplast 30:61–67. https://doi.org/10.1016/j.arth.2014.07.036
doi: 10.1016/j.arth.2014.07.036
Girard J, Lons A, Ramdane N, Putman S (2018) Hip resurfacing before 50 years of age: a prospective study of 979 hips with a mean follow-up of 5.1 years. Orthop Traumatology: Surg Res 104:295–299. https://doi.org/10.1016/j.otsr.2017.10.018
doi: 10.1016/j.otsr.2017.10.018
Konan S, Waugh C, Ohly N et al (2021) Mid-term results of a prospective randomised controlled trial comparing large-head metal-on-metal hip replacement to hip resurfacing using patient-reported outcome measures and objective functional task-based outcomes. HIP Int 31:637–643. https://doi.org/10.1177/1120700020919671
doi: 10.1177/1120700020919671 pubmed: 32390475
Vendittoli P-A, Shahin M, Rivière C et al (2020) Hip resurfacing compared with 28-mm metal-on-metal total hip replacement: a randomized study with 15 years of Follow-up*. J Bone Joint Surg 102:80–90. https://doi.org/10.2106/JBJS.20.00030
doi: 10.2106/JBJS.20.00030 pubmed: 32554999
Palazzuolo M, Antoniadis A, Delaune L et al (2021) Comparison of the long-term cause of failure and survivorship of four hundred and twenty seven metal-on-metal hip arthroplasties: resurfacing versus large head total hip arthroplasty. Int Orthop (SICOT) 45:3075–3081. https://doi.org/10.1007/s00264-021-05044-y
doi: 10.1007/s00264-021-05044-y
Lons A, Arnould A, Pommepuy T et al (2015) Excellent short-term results of hip resurfacing in a selected population of young patients. Orthop Traumatology: Surg Res 101:661–665. https://doi.org/10.1016/j.otsr.2015.07.011
doi: 10.1016/j.otsr.2015.07.011
Pollard TCB, Baker RP, Eastaugh-Waring SJ, Bannister GC, FIVE- TO SEVEN-YEAR COMPARISON OF HYBRID TOTAL HIP ARTHROPLASTY AND METAL-ON-METAL RESURFACING (2006) Treatment of the young active patient with osteoarthritis of the hip: a. J Bone Joint Surg Br Volume 88–B:592–600. https://doi.org/10.1302/0301-620X.88B5.17354
doi: 10.1302/0301-620X.88B5.17354
McBryde CW, Shears E, O’Hara JN, Pynsent PB (2008) Metal-on-metal hip resurfacing in developmental dysplasia: a CASE-CONTROL STUDY. J Bone Joint Surg Br Volume 90–B:708–714. https://doi.org/10.1302/0301-620X.90B6.20026
doi: 10.1302/0301-620X.90B6.20026
Murray DW, Grammatopoulos G, Pandit H et al (2012) The ten-year survival of the Birmingham hip resurfacing: an independent series. J Bone Joint Surg Br Volume 94–B:1180–1186. https://doi.org/10.1302/0301-620X.94B9.29462
doi: 10.1302/0301-620X.94B9.29462
Treacy RBC, McBryde CW, Shears E, Pynsent PB (2011) Birmingham hip resurfacing: a MINIMUM FOLLOW-UP OF TEN YEARS. The Journal of bone and joint surgery British volume. 93–B:27–33. https://doi.org/10.1302/0301-620X.93B1.24134
Coulter G, Young DA, Dalziel RE, Shimmin AJ (2012) Birmingham hip resurfacing at a mean of ten years: results from an independent centre. J Bone Joint Surg Br Volume 94–B:315–321. https://doi.org/10.1302/0301-620X.94B3.28185
doi: 10.1302/0301-620X.94B3.28185
Holland JP, Langton DJ, Hashmi M (2012) Ten-year clinical, radiological and metal ion analysis of the Birmingham hip resurfacing: from a single, non-designer surgeon. J Bone Joint Surg Br Volume 94–B:471–476. https://doi.org/10.1302/0301-620X.94B4.27895
doi: 10.1302/0301-620X.94B4.27895
Annual R (2016) AOANJRR. 2016. https://aoanjrr.sahmri.com/annual-reports-2016 (date last accessed 15 February 2023)
Amstutz HC, Le Duff MJ (2021) The 20-year results of the first 400 Conserve Plus hip resurfacing arthroplasties. Bone Joint J 103–B:25–32. https://doi.org/10.1302/0301-620X.103B7.BJJ-2020-2256.R1
doi: 10.1302/0301-620X.103B7.BJJ-2020-2256.R1 pubmed: 34192905
Trojani C Comments on: Hip resurfacing before 50 years of age: A prospective study of 979 hips with a mean follow-up of 5.1 years by, Girard J, Lons A, Ramdane N, Putman S (2018) published in Orthop Traumatol Surg Res. 2018;104(3):295–299. Orthopaedics & Traumatology: Surgery & Research 104:1297–1298. https://doi.org/10.1016/j.otsr.2018.07.005
Corten K, MacDonald SJ (2010) Clin Orthop Relat Res 468:351–357. https://doi.org/10.1007/s11999-009-1157-3 . Hip Resurfacing Data from National Joint Registries: What Do They Tell Us? What Do They Not Tell Us?
Stoney J, Graves SE, De Steiger RN et al (2020) Is the survivorship of Birmingham Hip Resurfacing Better Than selected conventional hip Arthroplasties in men younger than 65 years of age? A study from the Australian Orthopaedic Association National Joint Replacement Registry. Clin Orthop Relat Res 478:2625–2636. https://doi.org/10.1097/CORR.0000000000001453
doi: 10.1097/CORR.0000000000001453 pubmed: 32898048 pmcid: 7571983
Long WT, Dastane M, Harris MJ et al (2010) Failure of the Durom Metasul
doi: 10.1007/s11999-009-1071-8 pubmed: 19727987
Daniel J, Ziaee H, Kamali A et al (2010) Ten-year results of a double-heat-treated metal-on-metal hip resurfacing. J Bone Joint Surg Br Volume 92–B:20–27. https://doi.org/10.1302/0301-620X.92B1.21530
doi: 10.1302/0301-620X.92B1.21530
Falez F, Favetti F, Casella F et al (2011) Results of hip resurfacing. Int Orthop (SICOT) 35:239–243. https://doi.org/10.1007/s00264-010-1188-0
doi: 10.1007/s00264-010-1188-0
Hart AJ, Ilo K, Underwood R et al (2011) The relationship between the angle of version and rate of wear of retrieved metal-on-metal resurfacings: a PROSPECTIVE, CT-BASED STUDY. J Bone Joint Surg Br Volume 93–B:315–320. https://doi.org/10.1302/0301-620X.93B3.25545
doi: 10.1302/0301-620X.93B3.25545
Angadji A, Royle M, Collins SN, Shelton JC (2009) Influence of cup orientation on the wear performance of metal-on-metal hip replacements. Proc Inst Mech Eng H 223:449–457. https://doi.org/10.1243/09544119JEIM518
doi: 10.1243/09544119JEIM518 pubmed: 19499835
De Haan R, Pattyn C, Gill HS et al (2008) Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement. J Bone Joint Surg Br Volume 90–B:1291–1297. https://doi.org/10.1302/0301-620X.90B10.20533
doi: 10.1302/0301-620X.90B10.20533
Amstutz HC, Le Duff MJ, Bhaurla SK (2017) Risk factors for wear-related failures after hip resurfacing in patients with a low contact patch to rim distance. Bone Joint J 99–B:865–871. https://doi.org/10.1302/0301-620X.99B7.BJJ-2016-1369.R1
doi: 10.1302/0301-620X.99B7.BJJ-2016-1369.R1 pubmed: 28663390
Penny JØ, Ovesen O, Varmarken J-E, Overgaard S (2013) Similar range of motion and function after resurfacing large-head or standard total hip arthroplasty. Acta Orthop 84:246–253. https://doi.org/10.3109/17453674.2013.788435
doi: 10.3109/17453674.2013.788435 pubmed: 23530872 pmcid: 3715815
Borgwardt A, Borgwardt L, Zerahn B et al (2018) A Randomized Seven-Year study on performance of the Stemmed Metal M2a-Magnum and ceramic C2a-Taper, and the Resurfacing ReCap hip implants. J Arthroplasty 33:1412–1420. https://doi.org/10.1016/j.arth.2017.11.061
doi: 10.1016/j.arth.2017.11.061 pubmed: 29276121
Costa ML, Achten J, Foguet P et al (2018) Comparison of hip function and quality of life of total hip arthroplasty and resurfacing arthroplasty in the treatment of young patients with arthritis of the hip joint at 5 years. BMJ Open 8:e018849. https://doi.org/10.1136/bmjopen-2017-018849
doi: 10.1136/bmjopen-2017-018849 pubmed: 29530907 pmcid: 5879574
Hersnaes PN, Gromov K, Otte KS et al (2021) Harris hip score and SF-36 following metal-on-metal total hip arthroplasty and hip resurfacing - a randomized controlled trial with 5-years follow up including 75 patients. BMC Musculoskelet Disord 22:781. https://doi.org/10.1186/s12891-021-04671-1
doi: 10.1186/s12891-021-04671-1 pubmed: 34511090 pmcid: 8436430
Kostretzis L, Lavigne M, Kiss M-O et al (2021) Despite higher revision rate, MoM large-head THA offers better clinical scores than HR: 14-year results from a randomized controlled trial involving 48 patients. BMC Musculoskelet Disord 22:400. https://doi.org/10.1186/s12891-021-04286-6
doi: 10.1186/s12891-021-04286-6 pubmed: 33941155 pmcid: 8091753

Auteurs

Pierangelo Za (P)

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21 - 00128, Roma, Italy.
Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128, Roma, Italy.

Carlo Casciaro (C)

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21 - 00128, Roma, Italy.
Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128, Roma, Italy.

Giuseppe Francesco Papalia (GF)

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21 - 00128, Roma, Italy. g.papalia@policlinicocampus.it.
Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128, Roma, Italy. g.papalia@policlinicocampus.it.

Francesco Rosario Parisi (FR)

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21 - 00128, Roma, Italy.
Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128, Roma, Italy.

Umile Giuseppe Longo (UG)

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21 - 00128, Roma, Italy.
Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128, Roma, Italy.

Francesco Falez (F)

Department of Orthopaedics and Traumatology, S. Filippo Neri Hospital, ASL Roma 1, Rome, Italy.

Rocco Papalia (R)

Department of Orthopaedic and Trauma Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo, 21 - 00128, Roma, Italy.
Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200 - 00128, Roma, Italy.

Classifications MeSH