Sociodemographic and clinical features related to hepatitis B virus infection among rejected blood donors in Luanda, Angola.

Angola HBV infection HBsAg blood donors liver damage

Journal

Health science reports
ISSN: 2398-8835
Titre abrégé: Health Sci Rep
Pays: United States
ID NLM: 101728855

Informations de publication

Date de publication:
Aug 2024
Historique:
received: 23 04 2024
revised: 12 07 2024
accepted: 19 07 2024
medline: 7 8 2024
pubmed: 7 8 2024
entrez: 7 8 2024
Statut: epublish

Résumé

Hepatitis B virus (HBV) remains a public health concern. Blood donors screened for HBV surface antigen (HBsAg) along with aspartate transaminase (AST)/alanine aminotransferase (ALT) could play a key in providing safe blood products. We investigated the features related to HBV infection among rejected blood donors in Luanda, Angola. This was a cross-sectional study conducted with 164 rejected donors. Donors were screened for HBsAg from March to May 2022. Overall, 63.4% tested positive for HBV. The mean age of the HBV-positive (29.2 ± 8.02) was lower than the HBV-negative (33.9 ± 10.0) ( Our findings indicated the failure of viral hepatitis control measures. Authorities should consider including HBV nucleic acid testing to ensure early identification of HBV in Angola.

Sections du résumé

Background UNASSIGNED
Hepatitis B virus (HBV) remains a public health concern. Blood donors screened for HBV surface antigen (HBsAg) along with aspartate transaminase (AST)/alanine aminotransferase (ALT) could play a key in providing safe blood products. We investigated the features related to HBV infection among rejected blood donors in Luanda, Angola.
Methods UNASSIGNED
This was a cross-sectional study conducted with 164 rejected donors. Donors were screened for HBsAg from March to May 2022. Overall, 63.4% tested positive for HBV.
Results UNASSIGNED
The mean age of the HBV-positive (29.2 ± 8.02) was lower than the HBV-negative (33.9 ± 10.0) (
Conclusions UNASSIGNED
Our findings indicated the failure of viral hepatitis control measures. Authorities should consider including HBV nucleic acid testing to ensure early identification of HBV in Angola.

Identifiants

pubmed: 39108675
doi: 10.1002/hsr2.2287
pii: HSR22287
pmc: PMC11300953
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e2287

Informations de copyright

© 2024 The Author(s). Health Science Reports published by Wiley Periodicals LLC.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Domingos Jandondo (D)

Centro de Investigação em Saúde de Angola (CISA) Caxito Angola.
Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.

Victor Pimentel (V)

Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT Universidade NOVA de Lisboa, UNL Lisboa Portugal.

João Vigário (J)

Instituto Nacional de Sangue (INS) Ministério da Saúde Luanda Angola.

Pedro Vienga (P)

Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.

Joana M K Sebastião (JMK)

Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.

Anabela Mateus (A)

Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.

Felícia Comandante (F)

Instituto Nacional de Sangue (INS) Ministério da Saúde Luanda Angola.

Euclides Sacomboio (E)

Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.
Instituto de Ciências da Saúde (ICISA) Universidade Agostinho Neto (UAN) Luanda Angola.

Ana Abecasis (A)

Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT Universidade NOVA de Lisboa, UNL Lisboa Portugal.

Eunice Manico (E)

Instituto Nacional de Sangue (INS) Ministério da Saúde Luanda Angola.

Deodete Machado (D)

Instituto Nacional de Sangue (INS) Ministério da Saúde Luanda Angola.

Zinga David (Z)

Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.

Jocelyne Neto de Vasconcelos (JN)

Centro de Investigação em Saúde de Angola (CISA) Caxito Angola.

Joana Morais (J)

Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.

Cruz S Sebastião (CS)

Centro de Investigação em Saúde de Angola (CISA) Caxito Angola.
Instituto Nacional de Investigação em Saúde (INIS) Luanda Angola.
Global Health and Tropical Medicine, GHTM, Associate Laboratory in Translation and Innovation Towards Global Health, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT Universidade NOVA de Lisboa, UNL Lisboa Portugal.
Instituto de Ciências da Saúde (ICISA) Universidade Agostinho Neto (UAN) Luanda Angola.

Classifications MeSH