Elimination patterns of dimetridazole in egg of laying hens and tissues of broiler after oral administration.
HPLC-MS/MS
broiler
dimetridazole
laying hens
residue elimination
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2024
2024
Historique:
received:
20
06
2024
accepted:
12
07
2024
medline:
7
8
2024
pubmed:
7
8
2024
entrez:
7
8
2024
Statut:
epublish
Résumé
Dimetridazole (DMZ) is a broad-spectrum anti-anaerobic and antiprotozoal drug extensively used for the control of blackhead disease in poultry (especially turkeys). The presence of DMZ and its metabolites in animal food poses potential risks to human health. In this study, we developed a high-performance liquid chromatography tandem mass spectrometry (HPLC/MS-MS) method for the precise detection of DMZ and its metabolite 2-hydroxymethyl-1-methyl-5-nitroimidazole (HMMNI). Our results demonstrate a strong linear relationship (r
Identifiants
pubmed: 39109344
doi: 10.3389/fvets.2024.1451904
pmc: PMC11300331
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1451904Informations de copyright
Copyright © 2024 Mo, Wei, Bai, Long, Liu and Ding.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.