Barriers to access to antihypertensive medicines: insights from the HEARTS initiative in latin American and Caribbean region.

HEARTS initiative Hypertension access to medicines essential medicines lists pharmaceutical market analysis strategic fund

Journal

Journal of pharmaceutical policy and practice
ISSN: 2052-3211
Titre abrégé: J Pharm Policy Pract
Pays: England
ID NLM: 101627192

Informations de publication

Date de publication:
2024
Historique:
medline: 7 8 2024
pubmed: 7 8 2024
entrez: 7 8 2024
Statut: epublish

Résumé

Hypertension significantly impacts the global cardiovascular disease burden, presenting a pronounced challenge within Latin America and the Caribbean. The Pan American Health Organization's (PAHO) HEARTS initiative endeavours to meet this challenge by enhancing comprehensive cardiovascular risk management, inclusive of improved access to antihypertensive medications. This study scrutinises the challenges and barriers in accessing these medications, which are crucial for effective hypertension management in these regions. The research employed a two-phase approach: an initial analysis of National Essential Medicines Lists (NEMLs) from 22 countries involved in the HEARTS initiative for the presence of antihypertensive medications, followed by an in-depth pharmaceutical market analysis in six selected countries to evaluate the availability, pricing, and procurement practices of these medications. The study revealed notable inconsistencies in the inclusion of recommended antihypertensive medications across NEMLs, particularly the lack of fixed-dose combinations (FDCs). The market analysis brought to light significant limitations in medicine registration and substantial variations in pricing, which adversely impact the accessibility and affordability of essential antihypertensive treatments. Furthermore, an examination of procurement practices identified considerable diversity across countries, highlighting potential areas for optimisation, including the use of the PAHO Strategic Fund. The barriers to accessing essential antihypertensive medications in Latin America and the Caribbean are multifaceted, stemming from outmoded NEMLs, limited market availability of advised medications, and disparate procurement processes. Leveraging pooled procurement mechanisms such as the PAHO Strategic Fund, coupled with vital updates to NEMLs, stands to markedly improve both the accessibility and affordability of these treatments.

Identifiants

pubmed: 39109358
doi: 10.1080/20523211.2024.2379045
pii: 2379045
pmc: PMC11302458
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2379045

Informations de copyright

© 2024 Pan American Health Organization (PAHO/WHO). Published by Informa UK Limited, trading as Taylor & Francis.

Déclaration de conflit d'intérêts

No potential conflict of interest was reported by the author(s).

Auteurs

Kathiaja Miranda Souza (KM)

Special Program, Regional Revolving Funds, Pan American Health Organization, Washington, DC, USA.

Nora Giron (N)

Special Program, Regional Revolving Funds, Pan American Health Organization, Washington, DC, USA.

Juliana Vallini (J)

Special Program, Regional Revolving Funds, Pan American Health Organization, Washington, DC, USA.

Kemel Hallar (K)

Special Program, Regional Revolving Funds, Pan American Health Organization, Washington, DC, USA.

Pedro Ordunez (P)

Department of Non-Communicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, USA.

Andres Rosende (A)

Department of Non-Communicable Diseases and Mental Health, Pan American Health Organization, Washington, DC, USA.

Baudelio Ramírez Loya (BR)

Independent Consultant collaborating with the Special Program, Regional Revolving Funds, Pan American Health Organization, Mexico City, Mexico.

David Debrott Sánchez (DD)

Health Systems and Services, Primary Health Care and Integrated Services Delivery, Pan American Health Organization, Washington, DC, USA.

Christoper Lim (C)

Special Program, Regional Revolving Funds, Pan American Health Organization, Washington, DC, USA.

Classifications MeSH