DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability.
DNA methylation
Van der Woude syndrome
cleft lip and palate
epigenetics
lip pits
phenotypic variability
Journal
The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association
ISSN: 1545-1569
Titre abrégé: Cleft Palate Craniofac J
Pays: United States
ID NLM: 9102566
Informations de publication
Date de publication:
07 Aug 2024
07 Aug 2024
Historique:
medline:
7
8
2024
pubmed:
7
8
2024
entrez:
7
8
2024
Statut:
aheadofprint
Résumé
Van der Woude Syndrome (VWS) presents with combinations of lip pits (LP) and cleft lip and/or cleft palate (CL/P, CPO). VWS phenotypic heterogeneity even amongst relatives, suggests that epigenetic factors may act as modifiers. DNA methylation of CpG sites in For cleft type, blood samples showed higher We observed differential methylation in
Identifiants
pubmed: 39109995
doi: 10.1177/10556656241269495
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
10556656241269495Déclaration de conflit d'intérêts
Declaration of Conflicting InterestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.