Comparing the efficacy and safety of microneedling and its combination with other treatments in patients with acne scars: a network meta-analysis of randomized controlled trials.
Humans
Acne Vulgaris
/ complications
Randomized Controlled Trials as Topic
Treatment Outcome
Combined Modality Therapy
/ methods
Cicatrix
/ etiology
Network Meta-Analysis
Needles
/ adverse effects
Patient Satisfaction
Chemexfoliation
/ methods
Dry Needling
/ methods
Hyaluronic Acid
/ administration & dosage
Platelet-Rich Plasma
Laser Therapy
/ methods
Botulinum Toxins, Type A
/ administration & dosage
Percutaneous Collagen Induction
Acne scars
Chemical peels
Microneedling
Network meta-analysis
Platelet-rich plasma
Randomized controlled trials
Journal
Archives of dermatological research
ISSN: 1432-069X
Titre abrégé: Arch Dermatol Res
Pays: Germany
ID NLM: 8000462
Informations de publication
Date de publication:
07 Aug 2024
07 Aug 2024
Historique:
received:
19
06
2024
accepted:
30
07
2024
revised:
22
07
2024
medline:
7
8
2024
pubmed:
7
8
2024
entrez:
7
8
2024
Statut:
epublish
Résumé
This study aimed to analyze the efficacy and safety of microneedling (MN), both alone and in combination with other treatments, to refine the approach for treating acne scars using MN. We systematically searched Pubmed, Cochrane Library, Embase, and Web of Science for randomized controlled trials examining MN or its combinations in patients with acne scars. All statistical analyses were performed using Stata 18 software. A total of 24 studies involving 1546 participants were included. The analysis revealed that MN combined with chemical peels (CP) exhibited the best results in terms of degree of improvement, patient satisfaction, and treatment efficacy compared to other treatments examined, including MN alone, MN with hyaluronic acid (HA), MN with botulinum toxin‑A (TA), MN with platelet-rich plasma (PRP), PRP alone, CP, and laser therapy. The results for MN combined with additional treatments were obviously better than for MN alone. Side effects such as erythema, pain, and post-inflammatory hyperpigmentation showed no significant differences across all treatments assessed.
Identifiants
pubmed: 39110247
doi: 10.1007/s00403-024-03256-x
pii: 10.1007/s00403-024-03256-x
doi:
Substances chimiques
Hyaluronic Acid
9004-61-9
Botulinum Toxins, Type A
EC 3.4.24.69
Types de publication
Journal Article
Meta-Analysis
Comparative Study
Systematic Review
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
505Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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