KAT2A and KAT2B prevent double-stranded RNA accumulation and interferon signaling to maintain intestinal stem cell renewal.

Animals Signal Transduction RNA, Double-Stranded / metabolism Mice Stem Cells / metabolism Interferons / metabolism Mice, Knockout Histone Acetyltransferases / metabolism Intestinal Mucosa / metabolism Mitochondria / metabolism Cell Self Renewal / genetics Intestines / cytology

Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
09 Aug 2024
Historique:
medline: 8 8 2024
pubmed: 7 8 2024
entrez: 7 8 2024
Statut: ppublish

Résumé

Histone acetyltransferases

Identifiants

DOI: 10.1126/sciadv.adl1584 PMID: 39110797
pubmed: 39110797
doi: 10.1126/sciadv.adl1584
doi:

Substances chimiques

RNA, Double-Stranded 0
Interferons 9008-11-1
Histone Acetyltransferases EC 2.3.1.48

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eadl1584

Auteurs

Mai-Uyen Nguyen (MU)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0003-0936-2019

Jahangir Iqbal (J)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0002-9021-2271

Sarah Potgieter (S)

Department of Animal Sciences, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0002-1117-2612

Winston Huang (W)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0009-0009-6289-3928

Julie Pfeffer (J)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0009-0004-4753-017X

Sean Woo (S)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0009-0002-0108-1714

Caifeng Zhao (C)

Center for Advanced Biotechnology and Medicine, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0002-9957-1406

Matthew Lawlor (M)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0003-0700-5763

Richard Yang (R)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.

Rahma Rizly (R)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0009-0003-1922-2199

Angela Halstead (A)

Division of Gastroenterology, Departments of Medicine and Molecular Cell Biology, Washington University in St. Louis, St. Louis, MO, USA.
ORCID: 0000-0003-4892-0642

Sharon Dent (S)

The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
ORCID: 0000-0002-4824-3269

José B Sáenz (JB)

Division of Gastroenterology, Departments of Medicine and Molecular Cell Biology, Washington University in St. Louis, St. Louis, MO, USA.

Haiyan Zheng (H)

Center for Advanced Biotechnology and Medicine, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.

Zuo-Fei Yuan (ZF)

St. Jude Children's Research Hospital, Memphis, TN, USA.
ORCID: 0000-0003-1252-6766

Simone Sidoli (S)

Albert Einstein College of Medicine, The Bronx, NY, USA.
ORCID: 0000-0001-9073-6641

Christopher E Ellison (CE)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0002-0350-0962

Michael P Verzi (M)

Department of Genetics, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
Human Genetics Institute of New Jersey, Rutgers Cancer Institute of New Jersey, Rutgers Center for Lipid Research, Division of Environmental & Population Health Biosciences, EOHSI, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
ORCID: 0000-0003-4082-4330

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › ARN double brin › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Cellules › Cellules souches › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interférons › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Acyltransferases › Acetyltransferases › Lysine acetyltransferases › Histone acetyltransferases › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Tissus › Membranes › Muqueuse › Muqueuse intestinale › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Cellules › Structures cellulaires › Fractions subcellulaires › Mitochondries › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Division cellulaire › Auto-renouvellement cellulaire › KAT2A and KAT2B prevent double-stranded RNA...
questionsmedicales.fr › Système digestif › Tube digestif › Intestins › KAT2A and KAT2B prevent double-stranded RNA...