Structure-driven development of a biomimetic rare earth artificial metalloprotein.

Methylobacterium extorquens / enzymology Metalloproteins / chemistry Alcohol Dehydrogenase / metabolism Crystallography, X-Ray PQQ Cofactor / metabolism Biomimetic Materials / chemistry Metals, Rare Earth / chemistry Models, Molecular Lanthanum / chemistry
alcohol dehydrogenase metalloenzyme protein engineering pyrroloquinoline quinone rare earth elements

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
13 Aug 2024
Historique:
medline: 8 8 2024
pubmed: 8 8 2024
entrez: 8 8 2024
Statut: ppublish

Résumé

The 2011 discovery of the first rare earth-dependent enzyme in methylotrophic

Identifiants

DOI: 10.1073/pnas.2405836121 PMID: 39116128
pubmed: 39116128
doi: 10.1073/pnas.2405836121
doi:

Substances chimiques

Metalloproteins 0
Alcohol Dehydrogenase EC 1.1.1.1
PQQ Cofactor 72909-34-3
Metals, Rare Earth 0
Lanthanum 6I3K30563S

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2405836121

Subventions

Organisme : HHS | National Institutes of Health (NIH)
ID : GM138138
Organisme : Alfred P. Sloan Foundation (APSF)
ID : FG-2023-20581

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Peter J Thompson (PJ)

Center for Biophysics and Quantitative Biology, University of Illinois, Urbana-Champaign, Urbana, IL 61801.
ORCID: 0000-0003-3520-5113

David G Boggs (DG)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.
ORCID: 0000-0003-2946-9307

Charles A Wilson (CA)

Department of Chemistry, Materials Research Laboratory, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL 61801.

Austin T Bruchs (AT)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.

Uditha Velidandla (U)

Department of Chemistry, Materials Research Laboratory, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL 61801.

Jennifer Bridwell-Rabb (J)

Department of Chemistry, University of Michigan, Ann Arbor, MI 48109.
ORCID: 0000-0002-7437-6217

Lisa Olshansky (L)

Center for Biophysics and Quantitative Biology, University of Illinois, Urbana-Champaign, Urbana, IL 61801.
Department of Chemistry, Materials Research Laboratory, Beckman Institute for Advanced Science and Technology, University of Illinois Urbana-Champaign, Urbana, IL 61801.
ORCID: 0000-0003-1076-9318

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Classifications MeSH

questionsmedicales.fr › Bactéries › Proteobacteria › Alphaproteobacteria › Methylobacteriaceae › Methylobacterium › Methylobacterium extorquens › Structure-driven development of a biomimetic...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Métalloprotéines › Structure-driven development of a biomimetic...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › NAD (+) and NADP (+) dependent Alcohol oxidoreductases › Alcohol dehydrogenase › Structure-driven development of a biomimetic...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Cristallographie aux rayons X › Structure-driven development of a biomimetic...
questionsmedicales.fr › Enzymes et coenzymes › Coenzymes › Cofacteur PQQ › Structure-driven development of a biomimetic...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Structure-driven development of a biomimetic...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Terres rares › Structure-driven development of a biomimetic...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles moléculaires › Structure-driven development of a biomimetic...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Terres rares › Lanthanides › Lanthane › Structure-driven development of a biomimetic...