Vestibular schwannoma microneurosurgery in patients over 70: a single institution experience and proposal of a treatment algorithm.


Journal

Neurosurgical review
ISSN: 1437-2320
Titre abrégé: Neurosurg Rev
Pays: Germany
ID NLM: 7908181

Informations de publication

Date de publication:
08 Aug 2024
Historique:
received: 03 03 2024
accepted: 25 07 2024
revised: 25 07 2024
medline: 9 8 2024
pubmed: 9 8 2024
entrez: 8 8 2024
Statut: epublish

Résumé

Elderly patients with vestibular schwannoma (VS) are commonly observed. Retrospective analysis of 25 patients aging ≥ 70 operated on in our neurosurgical department for unilateral VS. The purpose of our study is to propose an algorithm for the treatment of VS in elderly patients. American Society of Anesthesiology (ASA) Grade I-II patients and Grade III with life-threatening tumors were enrolled. Karnofsky Performance Status Scale (KPS) was used for evalutation of the quality of life. The House-Brackmann (HB) scale for facial nerve (FN) outcome was used. Tumor size was categorized according to Koos' classification. A retrosigmoid approach was used in all cases, except one in which a translabyrinthine approach was performed. Surgical removal graduation: total (GTR), near total (NTR > 95%), subtotal (STR > 90%). The clinical and radiological follow-up period was set first at six months and then at one year after surgery. FN results evaluation was performed at one year, categorized according to House-Brackmann grades I-VI. Mean age: 74,4 years (70-83); 28% ASA I, 56% ASA II, 16% ASA III. Mean tumor size: 2,7 cm (1,5-4,2 cm). 68%, STR 32%. Mortality was zero. At last follow-up (one year after surgery) FN results were: HBI 81%, HBII 9.5%, HBIII 9.5%; HB IV 0%. Only 4 patients had preoperative HB IV, of whom one improved from HB IV to HB III. Transient complications occurred only in large VS. Re-growth of residue after STR was observed in 3 cases, treated with SRS in 2 cases and observed in 1. An algorithm of treatment of vestibular schwannoma in the elderly is proposed. In particular, in patients in general good conditions, age does not appear to be a major contraindication for microsurgery of VS. FN results at last follow-up are satisfactory and the complication rates are acceptable.

Sections du résumé

BACKGROUND BACKGROUND
Elderly patients with vestibular schwannoma (VS) are commonly observed.
OBJECT OBJECTIVE
Retrospective analysis of 25 patients aging ≥ 70 operated on in our neurosurgical department for unilateral VS. The purpose of our study is to propose an algorithm for the treatment of VS in elderly patients.
METHODS METHODS
American Society of Anesthesiology (ASA) Grade I-II patients and Grade III with life-threatening tumors were enrolled. Karnofsky Performance Status Scale (KPS) was used for evalutation of the quality of life. The House-Brackmann (HB) scale for facial nerve (FN) outcome was used. Tumor size was categorized according to Koos' classification. A retrosigmoid approach was used in all cases, except one in which a translabyrinthine approach was performed. Surgical removal graduation: total (GTR), near total (NTR > 95%), subtotal (STR > 90%). The clinical and radiological follow-up period was set first at six months and then at one year after surgery. FN results evaluation was performed at one year, categorized according to House-Brackmann grades I-VI.
RESULTS RESULTS
Mean age: 74,4 years (70-83); 28% ASA I, 56% ASA II, 16% ASA III. Mean tumor size: 2,7 cm (1,5-4,2 cm).
GTR/NTR UNASSIGNED
68%, STR 32%. Mortality was zero. At last follow-up (one year after surgery) FN results were: HBI 81%, HBII 9.5%, HBIII 9.5%; HB IV 0%. Only 4 patients had preoperative HB IV, of whom one improved from HB IV to HB III. Transient complications occurred only in large VS. Re-growth of residue after STR was observed in 3 cases, treated with SRS in 2 cases and observed in 1.
CONCLUSIONS CONCLUSIONS
An algorithm of treatment of vestibular schwannoma in the elderly is proposed. In particular, in patients in general good conditions, age does not appear to be a major contraindication for microsurgery of VS. FN results at last follow-up are satisfactory and the complication rates are acceptable.

Identifiants

pubmed: 39117744
doi: 10.1007/s10143-024-02615-6
pii: 10.1007/s10143-024-02615-6
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

410

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Silvia Michelini (S)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Alberto Campione (A)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Ettore Carpineta (E)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Flavia Fraschetti (F)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Carlo Giacobbo Scavo (CG)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Fabio Boccacci (F)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Guglielmo Cacciotti (G)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Giovanni Stati (G)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Raffaelino Roperto (R)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Amer A Alomari (AA)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy.

Luciano Mastronardi (L)

Department of Neurosurgery, San Filippo Neri Hospital/ASLRoma1, Rome, Italy. mastronardinch@gmail.com.

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