A Volume-Adjustable Artificial Womb for Extremely Preterm Infants.
adjustable silicone sac
artificial amniotic sac
artificial womb
extremely preterm infant
perinatal life support
Journal
Transplant international : official journal of the European Society for Organ Transplantation
ISSN: 1432-2277
Titre abrégé: Transpl Int
Pays: Switzerland
ID NLM: 8908516
Informations de publication
Date de publication:
2024
2024
Historique:
received:
04
03
2024
accepted:
24
06
2024
medline:
9
8
2024
pubmed:
9
8
2024
entrez:
9
8
2024
Statut:
epublish
Résumé
More than 13 million children are born preterm annually. Prematurity-related mortality accounts for 0.9 million deaths worldwide. The majority of those affected are Extremely Preterm Infants (gestational age less than 28 weeks). Immaturity causes organ failure and specific morbidities like germinal matrix hemorrhage, bronchopulmonary dysplasia, and necrotizing enterocolitis. Artificial womb and placenta technologies address these issues. As a bridge-to-life technology, they provide a liquid environment to allow organ maturation under more physiological conditions. The proposed artificial womb can adapt to fetal growth. Volume adjustment is achieved by removing fluid from the interspace between an inner and outer chamber. Results of the
Identifiants
pubmed: 39119064
doi: 10.3389/ti.2024.12947
pii: 12947
pmc: PMC11306982
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
12947Informations de copyright
Copyright © 2024 Heyer, Schubert, Seitz, Steinle, Arens, Orlikowsky, Steinseifer, Schmitz-Rode, Jansen and Schoberer.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.