FGF23-secreting sinonasal tumour presenting with acute subdural haemorrhage and tumour-induced osteomalacia.
Humans
Fibroblast Growth Factor-23
Osteomalacia
/ etiology
Female
Fibroblast Growth Factors
/ blood
Middle Aged
Hematoma, Subdural, Acute
/ etiology
Paranasal Sinus Neoplasms
/ complications
Paraneoplastic Syndromes
Neoplasms, Connective Tissue
/ surgery
Ethmoid Sinus
/ surgery
Magnetic Resonance Imaging
Neuro ITU
Neurosurgery
Osteomalacia
Otolaryngology / ENT
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
08 Aug 2024
08 Aug 2024
Historique:
medline:
10
8
2024
pubmed:
10
8
2024
entrez:
9
8
2024
Statut:
epublish
Résumé
A female in her 50s developed a headache, collapsed and was noted to have an acute atraumatic subdural haemorrhage (SDH) requiring surgical evacuation and intracranial pressure-directed therapy. Her background included recurrent epistaxis, severe generalised bone pain and multiple insufficiency fractures and an undifferentiated autoimmune connective tissue disease. Chronic hypophosphataemia, elevated alkaline phosphatase and raised fibroblast growth factor 23 (FGF23) were also noted. An MRI head and subsequent
Identifiants
pubmed: 39122377
pii: 17/8/e259439
doi: 10.1136/bcr-2023-259439
pii:
doi:
Substances chimiques
Fibroblast Growth Factor-23
7Q7P4S7RRE
FGF23 protein, human
0
Fibroblast Growth Factors
62031-54-3
Types de publication
Journal Article
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.