Gastric Carcinogenesis and Potential Role of the Transient Receptor Potential Vanilloid 1 (TRPV1) Receptor: An Observational Histopathological Study.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 Jul 2024
Historique:
received: 10 07 2024
revised: 26 07 2024
accepted: 26 07 2024
medline: 10 8 2024
pubmed: 10 8 2024
entrez: 10 8 2024
Statut: epublish

Résumé

The potential role of the transient receptor potential Vanilloid 1 (TRPV1) non-selective cation channel in gastric carcinogenesis remains unclear. The main objective of this study was to evaluate TRPV1 expression in gastric cancer (GC) and precursor lesions compared with controls. Patient inclusion was based on a retrospective review of pathology records. Patients were subdivided into five groups:

Identifiants

pubmed: 39125864
pii: ijms25158294
doi: 10.3390/ijms25158294
pii:
doi:

Substances chimiques

TRPV Cation Channels 0
TRPV1 protein, human 0

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Research, Development and Innovation Office
ID : TKP2021-EGA-13

Auteurs

Sylvester R Groen (SR)

Department of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Daniel Keszthelyi (D)

Department of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Arpad Szallasi (A)

Department of Pathology and Experimental Cancer Research, Semmelweis University, 1083 Budapest, Hungary.

Jara A van Veghel (JA)

Department of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Annick M E Alleleyn (AME)

Department of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Kata Csekő (K)

Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.
HUN-REN Chronic Pain Research Group, University of Pécs, 7624 Pécs, Hungary.
National Laboratory for Drug Research and Development, 1117 Budapest, Hungary.

Zsuzsanna Helyes (Z)

Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, 7624 Pécs, Hungary.
HUN-REN Chronic Pain Research Group, University of Pécs, 7624 Pécs, Hungary.
National Laboratory for Drug Research and Development, 1117 Budapest, Hungary.

Iryna Samarska (I)

Department of Pathology, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Heike I Grabsch (HI)

Department of Pathology, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.
Division of Pathology and Data Analytics, Leeds Institute of Medical Research at St James's University, University of Leeds, Leeds LS2 9JT, UK.

Ad A M Masclee (AAM)

Department of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

Zsa Zsa R M Weerts (ZZRM)

Department of Gastroenterology and Hepatology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center+, 6629 HX Maastricht, The Netherlands.

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Classifications MeSH