Caffeine Protects Keratinocytes from

Caffeine / pharmacology Keratinocytes / drug effects Humans Antifungal Agents / pharmacology Arthrodermataceae / drug effects Microbial Sensitivity Tests Cell Wall / drug effects Tinea / drug therapy Chitin / pharmacology
Trichophyton mentagrophytes antidermatophytic caffeine dermatophytes

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
30 Jul 2024
Historique:
received: 22 06 2024
revised: 21 07 2024
accepted: 25 07 2024
medline: 10 8 2024
pubmed: 10 8 2024
entrez: 10 8 2024
Statut: epublish

Résumé

Caffeine affords several beneficial effects on human health, acting as an antioxidant, anti-inflammatory agent, and analgesic. Caffeine is widely used in cosmetics, but its antimicrobial activity has been scarcely explored, namely against skin infection agents. Dermatophytes are the most common fungal agents of human infection, mainly of skin infections. This work describes the in vitro effect of caffeine during keratinocyte infection by

Identifiants

DOI: 10.3390/ijms25158303 PMID: 39125871
pubmed: 39125871
pii: ijms25158303
doi: 10.3390/ijms25158303
pii:
doi:

Substances chimiques

Caffeine 3G6A5W338E
Antifungal Agents 0
Chitin 1398-61-4

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Diogo M da Fonseca (DM)

FMUC-Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal.
CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.

Lisa Rodrigues (L)

CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
ORCID: 0000-0001-9898-2409

José Sousa-Baptista (J)

FMUC-Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal.
CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
ORCID: 0000-0003-2726-1043

Félix Marcos-Tejedor (F)

Department of Medical Sciences, Faculty of Health Sciences, University of Castilla-La Mancha, 45600 Talavera de la Reina, Toledo, Spain.
ORCID: 0000-0003-4696-4705

Marta Mota (M)

FMUC-Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal.
CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.

Rodrigo A Cunha (RA)

FMUC-Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal.
CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
ORCID: 0000-0003-2550-6422

Chantal Fernandes (C)

CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
ORCID: 0000-0001-7865-9946

Teresa Gonçalves (T)

FMUC-Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504 Coimbra, Portugal.
CNC-UC-Center for Neuroscience and Cell Biology of Coimbra, University of Coimbra, 3004-504 Coimbra, Portugal.
CIBB-Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, 3004-504 Coimbra, Portugal.
ORCID: 0000-0001-9347-0535

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Purines › Purinones › Xanthines › Caféine › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Cellules › Cellules épithéliales › Kératinocytes › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antifongiques › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Eucaryotes › Champignons › Ascomycota › Onygenales › Arthrodermataceae › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Cellules › Structures cellulaires › Paroi cellulaire › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Infections de la peau › Mycoses cutanées › Teigne › Caffeine Protects Keratinocytes from
questionsmedicales.fr › Glucides › Polyosides › Chitine › Caffeine Protects Keratinocytes from