Epizootic Hemorrhagic Disease Agar Gel Immunodiffusion Assay.

Agar gel Bluetongue Cross-reactivity Epizootic hemorrhagic disease Immunodiffusion Precipitation line

Journal

Methods in molecular biology (Clifton, N.J.)
ISSN: 1940-6029
Titre abrégé: Methods Mol Biol
Pays: United States
ID NLM: 9214969

Informations de publication

Date de publication:
2024
Historique:
medline: 10 8 2024
pubmed: 10 8 2024
entrez: 10 8 2024
Statut: ppublish

Résumé

Agar gel immunodiffusion assay (AGID) is a laboratory test which detects specific antigen-antibody interactions by the development of visible precipitation lines in a semisolid matrix. Here we describe the preparation of agar gel plates, the method to test serum samples by AGID for the presence of EHDV antibodies, and the interpretation of test results. This test has known cross-reactivity to bluetongue antibodies; therefore positive samples by this assay require additional confirmatory testing; generally, its use should be limited to healthy animal attestations where required.

Identifiants

pubmed: 39126628
doi: 10.1007/978-1-0716-4035-7_8
doi:

Substances chimiques

Agar 9002-18-0
Antibodies, Viral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

137-143

Informations de copyright

© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Références

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Auteurs

Mia Kim Torchetti (MK)

USDA APHIS, National Veterinary Services Laboratories, Iowa, USA. mia.kim.torchetti@usda.gov.

Abaineh Endalew (A)

USDA APHIS, National Veterinary Services Laboratories, Iowa, USA.

Albert Van Geelen (A)

USDA APHIS, National Veterinary Services Laboratories, Iowa, USA.

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Classifications MeSH