IrCytoToxDB: a dataset of iridium(III) complexes cytotoxicities against various cell lines.
Journal
Scientific data
ISSN: 2052-4463
Titre abrégé: Sci Data
Pays: England
ID NLM: 101640192
Informations de publication
Date de publication:
10 Aug 2024
10 Aug 2024
Historique:
received:
04
04
2024
accepted:
02
08
2024
medline:
11
8
2024
pubmed:
11
8
2024
entrez:
10
8
2024
Statut:
epublish
Résumé
Iridium(III) complexes nowadays became rising stars in various health-related applications. Thus, there is a necessity to assess cytotoxicity of the synthesized molecules against cancer/normal cell lines. In this report, we present a dataset of 2694 experimental cytotoxicity values of 803 iridium complexes against 127 different cell lines. We specify the experimental conditions and provide representation of the complexes molecules in machine-readable format. The dataset provides a starting point for exploration of new iridium-based cellular probes and opens new possibilities for predictions of toxicities and data-driven generation of new organometallic anticancer agents.
Identifiants
pubmed: 39127782
doi: 10.1038/s41597-024-03735-w
pii: 10.1038/s41597-024-03735-w
doi:
Substances chimiques
Iridium
44448S9773
Antineoplastic Agents
0
Coordination Complexes
0
Types de publication
Dataset
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
870Informations de copyright
© 2024. The Author(s).
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