Precision Medicine in Cytopathology.

Humans Precision Medicine Biomarkers, Tumor / genetics Neoplasms / pathology Cytodiagnosis / methods Cytology
Ancillary testing Cytopathology Immunohistochemistry Next-generation sequencing Precision medicine Predictive biomarkers

Journal

Surgical pathology clinics
ISSN: 1875-9157
Titre abrégé: Surg Pathol Clin
Pays: United States
ID NLM: 101491209

Informations de publication

Date de publication:
Sep 2024
Historique:
medline: 12 8 2024
pubmed: 12 8 2024
entrez: 12 8 2024
Statut: ppublish

Résumé

Over the last decade, cancer diagnostics has undergone a notable transformation with increasing complexity. Minimally invasive diagnostic tests, driven by advanced imaging and early detection protocols, are redefining patient care and reducing the need for more invasive procedures. Modern cytopathologists now safeguard patient samples for vital biomarker and molecular testing. In this article, we explore ancillary testing modalities and the role of biomarkers in organ-specific contexts, underscoring the transformative impact of precision medicine. Finally, the advent of more than 80 Food and Drug Administration-approved predictive biomarkers signals a new era, guiding cancer care toward personalized and targeted strategies.

Identifiants

DOI: 10.1016/j.path.2024.04.002 PMID: 39129134
pubmed: 39129134
pii: S1875-9181(24)00013-8
doi: 10.1016/j.path.2024.04.002
pii:
doi:

Substances chimiques

Biomarkers, Tumor 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

329-345

Informations de copyright

Copyright © 2024 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Acknowledgments Author DBA and this manuscript were supported by the Biospecimen Procurement & Translational Pathology Shared Resource Facility of the University of Kentucky Markey Cancer Center (P30CA177558). Disclosure The other authors have no relevant conflicts of interest to disclose.

Auteurs

Dava W Piecoro (DW)

Department of Pathology and Laboratory Medicine, 800 Rose Street, MS117, University of Kentucky College of Medicine, Lexington, KY 40536, USA.

Derek B Allison (DB)

Department of Pathology and Laboratory Medicine, 800 Rose Street, MS117, University of Kentucky College of Medicine, Lexington, KY 40536, USA; Markey Cancer Center, Lexington, KY 40536, USA; Department of Urology, University of Kentucky College of Medicine, Lexington, KY 40536, USA. Electronic address: Derek.Allison@uky.edu.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Precision Medicine in Cytopathology.
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Precision Medicine in Cytopathology.
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Marqueurs biologiques tumoraux › Precision Medicine in Cytopathology.
questionsmedicales.fr › Tumeurs › Precision Medicine in Cytopathology.
questionsmedicales.fr › Techniques d'investigation › Techniques cytologiques › Cytodiagnostic › Precision Medicine in Cytopathology.
questionsmedicales.fr › Professions de santé › Médecine › Anatomopathologie › Anatomopathologie clinique › Cytologie › Precision Medicine in Cytopathology.