Optogenetic control of phosphate-responsive genes using single component fusion proteins in
Journal
bioRxiv : the preprint server for biology
ISSN: 2692-8205
Titre abrégé: bioRxiv
Pays: United States
ID NLM: 101680187
Informations de publication
Date de publication:
03 Aug 2024
03 Aug 2024
Historique:
medline:
12
8
2024
pubmed:
12
8
2024
entrez:
12
8
2024
Statut:
epublish
Résumé
Blue light illumination can be detected by Light-Oxygen-Voltage (LOV) photosensing proteins and translated into a range of biochemical responses, facilitating the generation of novel optogenetic tools to control cellular function. Here we develop new variants of our previously described VP-EL222 light-dependent transcription factor and apply them to study the phosphate-responsive signaling (
Identifiants
pubmed: 39131330
doi: 10.1101/2024.08.02.605841
pmc: PMC11312615
pii:
doi:
Types de publication
Journal Article
Preprint
Langues
eng