Binding of cortical functional modules by synchronous high-frequency oscillations.


Journal

Nature human behaviour
ISSN: 2397-3374
Titre abrégé: Nat Hum Behav
Pays: England
ID NLM: 101697750

Informations de publication

Date de publication:
12 Aug 2024
Historique:
received: 25 08 2023
accepted: 09 07 2024
medline: 13 8 2024
pubmed: 13 8 2024
entrez: 12 8 2024
Statut: aheadofprint

Résumé

Whether high-frequency phase-locked oscillations facilitate integration ('binding') of information across widespread cortical areas is controversial. Here we show with intracranial electroencephalography that cortico-cortical co-ripples (~100-ms-long ~90 Hz oscillations) increase during reading and semantic decisions, at the times and co-locations when and where binding should occur. Fusiform wordform areas co-ripple with virtually all language areas, maximally from 200 to 400 ms post-word-onset. Semantically specified target words evoke strong co-rippling between wordform, semantic, executive and response areas from 400 to 800 ms, with increased co-rippling between semantic, executive and response areas prior to correct responses. Co-ripples were phase-locked at zero lag over long distances (>12 cm), especially when many areas were co-rippling. General co-activation, indexed by non-oscillatory high gamma, was mainly confined to early latencies in fusiform and earlier visual areas, preceding co-ripples. These findings suggest that widespread synchronous co-ripples may assist the integration of multiple cortical areas for sustained periods during cognition.

Identifiants

pubmed: 39134741
doi: 10.1038/s41562-024-01952-2
pii: 10.1038/s41562-024-01952-2
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : U.S. Department of Health & Human Services | National Institutes of Health (NIH)
ID : T32MH020002
Organisme : U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (NIMH)
ID : MH117155
Organisme : United States Department of Defense | United States Navy | Office of Naval Research (ONR)
ID : N00014-16-1-2829

Informations de copyright

© 2024. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Jacob C Garrett (JC)

Neurosciences Graduate Program, University of California, San Diego, La Jolla, CA, USA.

Ilya A Verzhbinsky (IA)

Neurosciences Graduate Program, University of California, San Diego, La Jolla, CA, USA.
Medical Scientist Training Program, University of California, San Diego, La Jolla, CA, USA.

Erik Kaestner (E)

Center for Multimodal Imaging and Genetics, University of California, San Diego, La Jolla, CA, USA.

Chad Carlson (C)

Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA.

Werner K Doyle (WK)

Department of Neurosurgery, New York University Langone School of Medicine, New York, NY, USA.

Orrin Devinsky (O)

Department of Neurology, New York University Langone School of Medicine, New York, NY, USA.

Thomas Thesen (T)

Department of Medical Education, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.

Eric Halgren (E)

Departments of Radiology and Neurosciences, University of California, San Diego, La Jolla, CA, USA. ehalgren@ucsd.edu.

Classifications MeSH