Preferences and uptake of home-based HIV self-testing for maternal retesting in Kenya.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2024
Historique:
received: 16 04 2024
accepted: 01 08 2024
medline: 13 8 2024
pubmed: 13 8 2024
entrez: 13 8 2024
Statut: epublish

Résumé

To compare preferences, uptake, and cofactors for unassisted home-based oral self-testing (HB-HIVST) versus clinic-based rapid diagnostic blood tests (CB-RDT) for maternal HIV retesting. Prospective cohort. Between November 2017 and June 2019, HIV-negative pregnant Kenyan women receiving antenatal care were enrolled and given a choice to retest with HB-HIVST or CB-RDT. Women were asked to retest between 36 weeks gestation and 1-week post-delivery if the last HIV test was <24 weeks gestation or at 6 weeks postpartum if ≥24 weeks gestation, and self-report on retesting at a 14-week postpartum. Overall, 994 women enrolled and 33% (n = 330) selected HB-HIVST. HB-HIVST was selected because it was private (n = 224, 68%), convenient (n = 211, 63%), and offered flexibility in the timing of retesting (n = 207, 63%), whereas CB-RDT was selected due to the trust of providers to administer the test (n = 510, 77%) and convenience of clinic testing (n = 423, 64%). Among 905 women who reported retesting at follow-up, 135 (15%) used HB-HIVST. Most (n = 595, 94%) who selected CB-RDT retested with this strategy, compared to 39% (n = 120) who selected HB-HIVST retesting with HB-HIVST. HB-HIVST retesting was more common among women with higher household income and those who may have been unable to test during pregnancy (both retested postpartum and delivered <37 weeks gestation) and less common among women who were depressed. Most women said they would retest in the future using the test selected at enrollment (99% [n = 133] HB-HIVST; 93% [n = 715] CB-RDT-RDT). While most women preferred CB-RDT for maternal retesting, HB-HIVST was acceptable and feasible and could be used to expand HIV retesting options.

Identifiants

pubmed: 39137189
doi: 10.1371/journal.pone.0302077
pii: PONE-D-24-11702
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0302077

Informations de copyright

Copyright: © 2024 Drake et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Alison L Drake (AL)

Department of Global Health, University of Washington, Seattle, WA, United States of America.
Department of Epidemiology, University of Washington, Seattle, WA, United States of America.

Wenwen Jiang (W)

Department of Epidemiology, University of Washington, Seattle, WA, United States of America.

Peninah Kitao (P)

Research and Programmes, Kenyatta National Hospital, Nairobi, Kenya.

Shiza Farid (S)

Department of Global Health, University of Washington, Seattle, WA, United States of America.

Barbra A Richardson (BA)

Department of Global Health, University of Washington, Seattle, WA, United States of America.
Department of Biostatistics, University of Washington, Seattle, WA, United States of America.

David A Katz (DA)

Department of Global Health, University of Washington, Seattle, WA, United States of America.

Anjuli D Wagner (AD)

Department of Global Health, University of Washington, Seattle, WA, United States of America.

Cheryl C Johnson (CC)

Department of Global HIV, Hepatitis and STI Programmes, World Health Organization, Geneva, Switzerland.

Daniel Matemo (D)

Research and Programmes, Kenyatta National Hospital, Nairobi, Kenya.

GraceJohn Stewart (G)

Department of Global Health, University of Washington, Seattle, WA, United States of America.
Department of Epidemiology, University of Washington, Seattle, WA, United States of America.
Department of Medicine, University of Washington, Seattle, WA, United States of America.
Department of Pediatrics, University of Washington, Seattle, WA, United States of America.

John Kinuthia (J)

Research and Programmes, Kenyatta National Hospital, Nairobi, Kenya.

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Classifications MeSH