The right posterior parietal cortex mediates spatial reorienting of attentional choice bias.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
13 Aug 2024
Historique:
received: 20 09 2022
accepted: 02 08 2024
medline: 14 8 2024
pubmed: 14 8 2024
entrez: 13 8 2024
Statut: epublish

Résumé

Attention facilitates behavior by enhancing perceptual sensitivity (sensory processing) and choice bias (decisional weighting) for attended information. Whether distinct neural substrates mediate these distinct components of attention remains unknown. We investigate the causal role of key nodes of the right posterior parietal cortex (rPPC) in the forebrain attention network in sensitivity versus bias control. Two groups of participants performed a cued attention task while we applied either inhibitory, repetitive transcranial magnetic stimulation (n = 28) or 40 Hz transcranial alternating current stimulation (n = 26) to the dorsal rPPC. We show that rPPC stimulation - with either modality - impairs task performance by selectively altering attentional modulation of bias but not sensitivity. Specifically, participants' bias toward the uncued, but not the cued, location reduced significantly following rPPC stimulation - an effect that was consistent across both neurostimulation cohorts. In sum, the dorsal rPPC causally mediates the reorienting of choice bias, one particular component of visual spatial attention.

Identifiants

pubmed: 39138185
doi: 10.1038/s41467-024-51283-z
pii: 10.1038/s41467-024-51283-z
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6938

Informations de copyright

© 2024. The Author(s).

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Auteurs

Ankita Sengupta (A)

Centre for Neuroscience, Indian Institute of Science, Bangalore, 560012, India.

Sanjna Banerjee (S)

Centre for Neuroscience, Indian Institute of Science, Bangalore, 560012, India.
Foundation of Art and Health India, Bangalore, 560066, India.

Suhas Ganesh (S)

Centre for Neuroscience, Indian Institute of Science, Bangalore, 560012, India.
Verily Life Sciences, San Francisco, CA, 94080, USA.

Shrey Grover (S)

Centre for Neuroscience, Indian Institute of Science, Bangalore, 560012, India.
Department of Psychological and Brain Sciences, Boston University, Boston, MA, 02215, USA.

Devarajan Sridharan (D)

Centre for Neuroscience, Indian Institute of Science, Bangalore, 560012, India. sridhar@iisc.ac.in.
Department of Computer Science and Automation, Indian Institute of Science, Bangalore, 560012, India. sridhar@iisc.ac.in.

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