Towards clinical application of freehand optical ultrasound imaging.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
13 08 2024
13 08 2024
Historique:
received:
27
05
2024
accepted:
09
08
2024
medline:
14
8
2024
pubmed:
14
8
2024
entrez:
13
8
2024
Statut:
epublish
Résumé
Freehand optical ultrasound (OpUS) imaging is an emerging ultrasound imaging paradigm that uses an array of fibre-optic, photoacoustic ultrasound sources and a single fibre-optic ultrasound detector to perform ultrasound imaging without the need for electrical components in the probe head. Previous freehand OpUS devices have demonstrated capability for real-time, video-rate imaging of clinically relevant targets, but have been hampered by poor ultrasound penetration, significant imaging artefacts and low frame rates, and their designs limited their clinical applicability. In this work we present a novel freehand OpUS imaging platform, including a fully mobile and compact acquisition console and an improved probe design. The novel freehand OpUS probe presented utilises optical waveguides to shape the generated ultrasound fields for improved ultrasound penetration depths, an extended fibre-optic bundle to improve system versatility and an overall ruggedised design with protective elements to improve probe handling and protect the internal optical components. This probe is demonstrated with phantoms and the first multi-participant in vivo imaging study conducted with freehand OpUS imaging probes, this represents several significant steps towards the clinical translation of freehand OpUS imaging.
Identifiants
pubmed: 39138339
doi: 10.1038/s41598-024-69826-1
pii: 10.1038/s41598-024-69826-1
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
18779Subventions
Organisme : The Engingeering and Physical Sciences Research Council (EPSRC)
ID : EP/T517793/1
Organisme : The Engingeering and Physical Sciences Research Council (EPSRC)
ID : EP/T517793/1
Organisme : The Rosetrees Trust
ID : PGS19-2/10006
Organisme : The Rosetrees Trust
ID : PGS19-2/10006
Organisme : Wellcome / EPSRC Centre for Interventional and Surgical Sciences
ID : 203145Z/16/Z
Organisme : Wellcome / EPSRC Centre for Interventional and Surgical Sciences
ID : 203145Z/16/Z
Organisme : Wellcome / EPSRC Centre for Interventional and Surgical Sciences
ID : 203145Z/16/Z
Organisme : Wellcome / EPSRC Centre for Interventional and Surgical Sciences
ID : 203145Z/16/Z
Organisme : Wellcome / EPSRC Centre for Interventional and Surgical Sciences
ID : 203145Z/16/Z
Organisme : European Research Council
ID : 741149
Pays : International
Organisme : Academy of Medical Sciences
ID : SBF007/100006
Pays : United Kingdom
Informations de copyright
© 2024. The Author(s).
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