Brief cycling intervals incrementally increase the number of hematopoietic stem and progenitor cells in human peripheral blood.
HSPC
exercise
interval cycling
natural killer cell
peripheral blood stem cell donation
transplantation
Journal
Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006
Informations de publication
Date de publication:
2024
2024
Historique:
received:
27
10
2023
accepted:
11
07
2024
medline:
14
8
2024
pubmed:
14
8
2024
entrez:
14
8
2024
Statut:
epublish
Résumé
Peripheral blood stem cell (PBSC) donation is the primary procedure used to collect hematopoietic stem and progenitor cells (HSPCs) for hematopoietic stem cell transplantation. Single bouts of exercise transiently enrich peripheral blood with HSPCs and cytolytic natural killer cells (CD56 In a randomised crossover study design, eleven males (mean ± SD: age 25 ± 7 years) undertook bouts of moderate intensity continuous exercise [MICE, 30 min, 65%-70% maximum heart rate (HR There was an increase in HSPC concentration after two intervals of LV-HIIE (Rest: 1.84 ± 1.55 vs. Interval 2: 2.94 ± 1.34, The results of the present study indicate that HIIE caused a more marked increase in HSPC and CD56
Identifiants
pubmed: 39139483
doi: 10.3389/fphys.2024.1327269
pii: 1327269
pmc: PMC11319260
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1327269Informations de copyright
Copyright © 2024 Pradana, Nijjar, Cox, Morgan, Podlogar, Lucas, Drayson, Kinsella and Wadley.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.