Brief cycling intervals incrementally increase the number of hematopoietic stem and progenitor cells in human peripheral blood.

HSPC exercise interval cycling natural killer cell peripheral blood stem cell donation transplantation

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2024
Historique:
received: 27 10 2023
accepted: 11 07 2024
medline: 14 8 2024
pubmed: 14 8 2024
entrez: 14 8 2024
Statut: epublish

Résumé

Peripheral blood stem cell (PBSC) donation is the primary procedure used to collect hematopoietic stem and progenitor cells (HSPCs) for hematopoietic stem cell transplantation. Single bouts of exercise transiently enrich peripheral blood with HSPCs and cytolytic natural killer cells (CD56 In a randomised crossover study design, eleven males (mean ± SD: age 25 ± 7 years) undertook bouts of moderate intensity continuous exercise [MICE, 30 min, 65%-70% maximum heart rate (HR There was an increase in HSPC concentration after two intervals of LV-HIIE (Rest: 1.84 ± 1.55 vs. Interval 2: 2.94 ± 1.34, The results of the present study indicate that HIIE caused a more marked increase in HSPC and CD56

Identifiants

pubmed: 39139483
doi: 10.3389/fphys.2024.1327269
pii: 1327269
pmc: PMC11319260
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1327269

Informations de copyright

Copyright © 2024 Pradana, Nijjar, Cox, Morgan, Podlogar, Lucas, Drayson, Kinsella and Wadley.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Fendi Pradana (F)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Nutrition Study Program, Faculty of Public Health, Tadulako University, Palu, Indonesia.

Tarondeep Nijjar (T)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Phoebe A Cox (PA)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Paul T Morgan (PT)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.
Department of Sport and Exercise Sciences, Manchester Metropolitan University, Manchester, United Kingdom.

Tim Podlogar (T)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Samuel J E Lucas (SJE)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Mark T Drayson (MT)

Clinical Immunology Service, University of Birmingham, Birmingham, United Kingdom.

Francesca A M Kinsella (FAM)

Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom.
Centre for Clinical Haematology, Queen Elizabeth Hospital, Birmingham, United Kingdom.

Alex J Wadley (AJ)

School of Sport, Exercise, and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom.

Classifications MeSH