Impact of radiological follow-up frequency on resected lung cancer: a propensity score matching analysis.

Lung cancer follow-up oncological outcomes radiological surveillance

Journal

Journal of thoracic disease

ISSN: 2072-1439

Titre abrégé: J Thorac Dis

Pays: China

ID NLM: 101533916

Informations de publication

Date de publication:
30 Jul 2024

Historique:

received: 28 12 2023

accepted: 26 04 2024

medline: 15 8 2024

pubmed: 15 8 2024

entrez: 15 8 2024

Statut: ppublish

Résumé

Despite advances in lung cancer treatment and the subsequent improvement in oncological outcomes, the optimal frequency of radiological follow-up remains unclear. Current recommendations lack consensus and do not consider individual patient characteristics and tumor factors. This study aimed to examine the impact of radiological follow-up frequency on oncological outcomes following lung cancer resection. A prospective multicenter study, involving patients who underwent anatomical lung resection in the GEVATS database between December 2016 and March 2018. The relationship between surveillance frequency and oncological outcomes was evaluated. Two groups were established based on follow-up frequency: low frequency (LF) and high frequency (HF). Subgroup analyses were performed based on tumor stage, histology, lymphadenectomy, and adjuvant therapy. Propensity score matching (PSM) was applied to balance the groups. A total of 1,916 patients were included in the study, LF 444 (23.17%), HF 1,472 (76.83%). Factors associated with HF surveillance included higher stage, adjuvant chemotherapy and adjuvant radiotherapy. Subanalyses were performed after PSM for various factors, revealing significant differences between LF and HF groups in cancer-specific survival among who received adjuvant therapy {LF 53.021 months [95% confidence interval (CI): 48.622-57.421] Findings suggest that high-frequency surveillance only improves survival outcomes in lung cancer patients who received adjuvant treatment or had squamous cell carcinoma. Therefore, future guidelines for lung cancer follow-up should consider individualizing the frequency of radiological surveillance based on patients' risk profiles.

Sections du résumé

Background UNASSIGNED

Methods UNASSIGNED

A prospective multicenter study, involving patients who underwent anatomical lung resection in the GEVATS database between December 2016 and March 2018. The relationship between surveillance frequency and oncological outcomes was evaluated. Two groups were established based on follow-up frequency: low frequency (LF) and high frequency (HF). Subgroup analyses were performed based on tumor stage, histology, lymphadenectomy, and adjuvant therapy. Propensity score matching (PSM) was applied to balance the groups.

Results UNASSIGNED

A total of 1,916 patients were included in the study, LF 444 (23.17%), HF 1,472 (76.83%). Factors associated with HF surveillance included higher stage, adjuvant chemotherapy and adjuvant radiotherapy. Subanalyses were performed after PSM for various factors, revealing significant differences between LF and HF groups in cancer-specific survival among who received adjuvant therapy {LF 53.021 months [95% confidence interval (CI): 48.622-57.421]

Conclusions UNASSIGNED

Findings suggest that high-frequency surveillance only improves survival outcomes in lung cancer patients who received adjuvant treatment or had squamous cell carcinoma. Therefore, future guidelines for lung cancer follow-up should consider individualizing the frequency of radiological surveillance based on patients' risk profiles.

Identifiants

DOI: 10.21037/jtd-23-1973 PMID: 39144331 PMC: PMC11320246

pubmed: 39144331

doi: 10.21037/jtd-23-1973

pii: jtd-16-07-4275

pmc: PMC11320246

doi:

Types de publication

Journal Article

Langues

eng

Pagination

4275-4285

Investigateurs

Borja Aguinagalde (B)

Miguel Jesús Arrarás (MJ)

Fernando Ascanio (F)

Ana Isabel Blanco Orozco (AI)

Marc Boada (M)

Sergio Bolufer (S)

Alberto Cabañero (A)

Isabel Cal (I)

Sergi Call (S)

Ángel Cilleruelo Ramos (Á)

Miguel Congregado (M)

Silvana Crowley Carrasco (SC)

Raúl Embún (R)

Elena Fernández-Martín (E)

Juan José Fibla Alfara (JJ)

Álvaro Fuentes-Martín (Á)

Santiago García-Barajas (S)

María Dolores García-Jiménez (MD)

Jose María García-Prim (JM)

Juan José Gelbenzu-Zazpe (JJ)

Carlos Fernando Giraldo-Ospina (CF)

David Gómez de Antonio (DG)

María Teresa Gómez Hernández (MT)

Jorge Hernández (J)

Florentino Hernando-Trancho (F)

Jennifer D Illana Wolf (JD)

Alberto Jáuregui Abularach (AJ)

Marcelo F Jimenez (MF)

Iker López Sanz (I)

Cipriano López García (C)

Marta López Porras (M)

Néstor J Martínez-Hernández (NJ)

Elisabeth Martínez-Téllez (E)

Roberto Mongil Poce (R)

Mario Montesinos Escalada (MM)

Nicolás Moreno (N)

Ramón Moreno-Basalobre (R)

Carme Obiols Fornell (C)

Florencio Quero-Valenzuela (F)

María Elena Ramírez-Gil (ME)

Ricard Ramos-Izquierdo (R)

José Luis Recuero (JL)

Íñigo Royo (Í)

Eduardo Rivo (E)

Alberto Rodríguez-Fuster (A)

David Sanchez Lorente (D)

Laura Sánchez Moreno (LS)

Julio Sesma Romero (J)

Carlos Simón (C)

Ana Isabel Triviño (AI)

Juan Carlos Trujillo-Reyes (JC)

Informations de copyright

Déclaration de conflit d'intérêts

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jtd.amegroups.com/article/view/10.21037/jtd-23-1973/coif). The authors have no conflicts of interest to declare.