Orthostatic


Journal

Transplant international : official journal of the European Society for Organ Transplantation
ISSN: 1432-2277
Titre abrégé: Transpl Int
Pays: Switzerland
ID NLM: 8908516

Informations de publication

Date de publication:
2024
Historique:
received: 24 04 2024
accepted: 11 07 2024
medline: 15 8 2024
pubmed: 15 8 2024
entrez: 15 8 2024
Statut: epublish

Résumé

The key goal in lung donation remains the improvement of graft preservation with the ultimate objective of increasing the number and quality of lung transplants (LTx). Therefore, in recent years the field of graft preservation focused on improving outcomes related to solid organ regeneration and restoration. In this contest Ex-Vivo Lung Perfusion (EVLP) plays a crucial role with the purpose to increase the donor pool availability transforming marginal and/or declined donor lungs suitable for transplantation. Aim of this proof of concept is to test the safety, suitability and feasibility of a new tilting dome for EVLP designed considering the dorsal lung areas as the "Achilles' heel" of the EVLP due to a more fluid accumulation than in the supine standard position.

Identifiants

pubmed: 39144835
doi: 10.3389/ti.2024.13178
pii: 13178
pmc: PMC11321966
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

13178

Informations de copyright

Copyright © 2024 Boffini, Costamagna, Marro, Simonato, Cassoni, Bertero, Fanelli, Barbero, Brazzi and Rinaldi.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Auteurs

Massimo Boffini (M)

Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Andrea Costamagna (A)

Anesthesiology and Intensive Care Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Matteo Marro (M)

Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Erika Simonato (E)

Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Paola Cassoni (P)

Pathology Unit, Medical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Luca Bertero (L)

Pathology Unit, Medical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Vito Fanelli (V)

Anesthesiology and Intensive Care Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Cristina Barbero (C)

Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Luca Brazzi (L)

Anesthesiology and Intensive Care Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

Mauro Rinaldi (M)

Cardiac Surgery Division, Surgical Sciences Department, Citta della Salute e della Scienza, University of Torino, Turin, Italy.

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Classifications MeSH