Glycated hemoglobin, type 2 diabetes, and poor diabetes control are positively associated with impulsivity changes in aged individuals with overweight or obesity and metabolic syndrome.
glycated hemoglobin (HbA1c)
impulsivity
insulin resistance (HOMA‐IR)
type 2 diabetes control
type 2 diabetes mellitus
Journal
Annals of the New York Academy of Sciences
ISSN: 1749-6632
Titre abrégé: Ann N Y Acad Sci
Pays: United States
ID NLM: 7506858
Informations de publication
Date de publication:
16 Aug 2024
16 Aug 2024
Historique:
medline:
16
8
2024
pubmed:
16
8
2024
entrez:
16
8
2024
Statut:
aheadofprint
Résumé
Impulsivity has been proposed to have an impact on glycemic dysregulation. However, it remains uncertain whether an unfavorable glycemic status could also contribute to an increase in impulsivity levels. This study aims to analyze associations of baseline and time-varying glycemic status with 3-year time-varying impulsivity in older adults at high risk of cardiovascular disease. A 3-year prospective cohort design was conducted within the PREDIMED-Plus-Cognition substudy. The total population includes 487 participants (mean age = 65.2 years; female = 50.5%) with overweight or obesity and metabolic syndrome. Insulin resistance (HOMA-IR), glycated hemoglobin (HbA1c), presence of type 2 diabetes mellitus, and type 2 diabetes control were evaluated. Impulsivity was measured using the Impulsive Behavior Scale questionnaire and various cognitive measurements. Impulsivity z-scores were generated to obtain Global, Trait, and Behavioral Impulsivity domains. Linear mixed models were used to study the longitudinal associations across baseline, 1-year, and 3-year follow-up visits. HOMA-IR was not significantly related to impulsivity. Participants with higher HbA1c levels, type 2 diabetes, and poor control of diabetes showed positive associations with the Global Impulsivity domain over time, and those with higher HbA1c levels were further related to increases in the Trait and Behavioral Impulsivity domains over the follow-up visits. These results suggest a potential positive feedback loop between impulsivity and glycemic-related dysregulation.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Instituto de Salud Carlos III
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ID : 2020PMF-PIPF-37
Organisme : Horizon 2020 Framework Programme
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ID : Ref 728018
Organisme : Horizon 2020 Framework Programme
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Organisme : Consejería de Salud y Bienestar Social, Junta de Andalucía
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Organisme : Ministerio de Ciencia e Innovacion, Madrid, Spain
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Organisme : Canadian Institutes of Health Research (CIHR)
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Informations de copyright
© 2024 The Author(s). Annals of the New York Academy of Sciences published by Wiley Periodicals LLC on behalf of The New York Academy of Sciences.
Références
Mischel, W., & Shoda, Y. (1995). A cognitive‐affective system theory of personality: Reconceptualizing situations, dispositions, dynamics, and invariance in personality structure. Psychological Review, 102(2), 246–268. https://doi.org/10.1037/0033‐295X.102.2.246
Svrakic, D. M., Przybeck, T. R., & Cloninger, C. R. (1992). Mood states and personality traits. Journal of Affective Disorders, 24(4), 217–226. https://doi.org/10.1016/0165‐0327(92)90106‐G
Harper, R. G. (2004). Personality‐guided therapy in behavioral medicine. American Psychological Association.
Moeller, F. G., Barratt, E. S., Dougherty, D. M., Schmitz, J. M., & Swann, A. C. (2001). Psychiatric aspects of impulsivity. American Journal of Psychiatry, 158(11), 1783–1793. https://doi.org/10.1176/appi.ajp.158.11.1783
Liu, M., Argyriou, E., & Cyders, M. A. (2020). Developmental considerations for assessment and treatment of impulsivity in older adults. Current Topics in Behavioral Neurosciences, 47, 165–177. https://doi.org/10.1007/7854_2019_1246
Hollander, E., & Rosen, J. (2000). Impulsivity. Journal of Psychopharmacology, 14(2_suppl1), S39–S44. https://doi.org/10.1177/02698811000142S106
Emery, R. L., & Levine, M. D. (2017). Questionnaire and behavioral task measures of impulsivity are differentially associated with body mass index: A comprehensive meta‐analysis. Psychological Bulletin, 143(8), 868–902. https://doi.org/10.1037/bul0000105
Garcia‐Garcia, I., Neseliler, S., Morys, F., Dadar, M., Yau, Y. H., Scala, S. G., Zeighami, Y., Sun, N., Collins, D. L., Vainik, U., & Dagher, A. (2022). Relationship between impulsivity, uncontrolled eating and body mass index: A hierarchical model. International Journal of Obesity, 46(1), 129–136.
van den, B., & Clark, C. (2021). The role of impulsivity on health behavior related to cardiovascular disease among young adults. Psychological Trauma: Theory, Research, Practice, and Policy, 13(3), 271–276. https://doi.org/10.1037/tra0000910
Emery, R. L., Levine, M. D., Creswell, K. G., Wright, A. G., Marsland, A. L., Matthews, K. A., Flory, J. D., & Manuck, S. B. (2020). Impulsivity and midlife cardiometabolic risk: The role of maladaptive health behaviors. Health Psychology, 39(8), 642–654. https://doi.org/10.1037/hea0000884
Boswell, R. G., & Grilo, C. M. (2021). General impulsivity in binge‐eating disorder. CNS Spectrums, 26(5), 538–544. https://doi.org/10.1017/S1092852920001674
Carr, M. M., Wiedemann, A. A., Macdonald‐Gagnon, G., & Potenza, M. N. (2021). Impulsivity and compulsivity in binge eating disorder: A systematic review of behavioral studies. Progress in Neuro‐Psychopharmacology & Biological Psychiatry, 110, 110318. https://doi.org/10.1016/j.pnpbp.2021.11031813
Herman, A. M., & Duka, T. (2019). Facets of impulsivity and alcohol use: What role do emotions play? Neuroscience & Biobehavioral Reviews, 106, 202–216. https://doi.org/10.1016/j.neubiorev.2018.08.011
Kozak, K., Lucatch, A. M., Lowe, D. J., Balodis, I. M., MacKillop, J., & George, T. P. (2019). The neurobiology of impulsivity and substance use disorders: Implications for treatment. Annals of the New York Academy of Sciences, 1451(1), 71–91. https://doi.org/10.1111/nyas.13977
Riby, L. M., Lai Teik Ong, D., Azmie, N. B. M., Ooi, E. L., Regina, C., Yeo, E. K. W., Massa, J., & Aquili, L. (2017). Impulsiveness, postprandial blood glucose, and glucoregulation affect measures of behavioral flexibility. Nutrition Research, 48, 65–75. https://doi.org/10.1016/j.nutres.2017.10.011
Hawkins, M. A., Gunstad, J., Calvo, D., & Spitznagel, M. B. (2016). Higher fasting glucose is associated with poorer cognition among healthy young adults. Health Psychology, 35(2), 199–202. https://doi.org/10.1037/hea0000248
Epstein, L. H., Paluch, R. A., Stein, J. S., Quattrin, T., Mastrandrea, L. D., Bree, K. A., Sze, Y. Y., Greenawald, M. H., Biondolillo, M. J., & Bickel, W. K. (2021). Delay discounting, glycemic regulation and health behaviors in adults with prediabetes. Behavioral Medicine, 47(3), 194–204. https://doi.org/10.1080/08964289.2020.1712581
Lebeau, G., Consoli, S. M., Le Bouc, R., Sola‐Gazagnes, A., Hartemann, A., Simon, D., Reach, G., Altman, J. J., Pessiglione, M., Limosin, F., & Lemogne, C. (2016). Delay discounting of gains and losses, glycemic control and therapeutic adherence in type 2 diabetes. Behavioural Processes, 132, 42–48. https://doi.org/10.1016/j.beproc.2016.09.006
Reach, G., Michault, A., Bihan, H., Paulino, C., Cohen, R., & Le Clésiau, H. (2011). Patients' impatience is an independent determinant of poor diabetes control. Diabetes & Metabolism, 37(6), 497–504. https://doi.org/10.1016/j.diabet.2011.03.004
Lansing, A. H., Stanger, C., Crochiere, R., Carracher, A., & Budney, A. (2017). Delay discounting and parental monitoring in adolescents with poorly controlled type 1 diabetes. Journal of Behavioral Medicine, 40(6), 864–874. https://doi.org/10.1007/s10865‐017‐9856‐9
Wainwright, K., Romanowich, P., & Crabtree, M. A. (2022). Associations between impulsivity and self‐care adherence in individuals diagnosed with Type 2 or prediabetes. PLoS ONE, 17(3), e0263961. https://doi.org/10.1371/journal.pone.0263961
Hadj‐Abo, A., Enge, S., Rose, J., Kunte, H., & Fleischhauer, M. (2020). Individual differences in impulsivity and need for cognition as potential risk or resilience factors of diabetes self‐management and glycemic control. PLoS ONE, 15(1), e0227995. https://doi.org/10.1371/journal.pone.0227995
Gailliot, M. T., & Baumeister, R. F. (2007). The physiology of willpower: Linking blood glucose to self‐control. Personality and Social Psychology Review, 11(4), 303–327. https://doi.org/10.1177/1088868307303030
Jorge, H., Duarte, I. C., Paiva, S., Relvas, A. P., & Castelo‐Branco, M. (2022). Abnormal responses in cognitive impulsivity circuits are associated with glycosylated hemoglobin trajectories in type 1 diabetes mellitus and impaired metabolic control. Diabetes & Metabolism, 46(6), 866–878. https://doi.org/10.4093/dmj.2021.0307
Eckstrand, K. L., Mummareddy, N., Kang, H., Cowan, R., Zhou, M., Zald, D., Silver, H. J., Niswender, K. D., & Avison, M. J. (2017). An insulin resistance associated neural correlate of impulsivity in type 2 diabetes mellitus. PLoS ONE, 12(12), e0189113. https://doi.org/10.1371/journal.pone.0189113
Eriksson, A. K., Gustavsson, J. P., Hilding, A., Granath, F., Ekbom, A., & Ostenson, C. G. (2012). Personality traits and abnormal glucose regulation in middle‐aged Swedish men and women. Diabetes Research and Clinical Practice, 95(1), 145–152. https://doi.org/10.1016/j.diabres.2011.10.003
Klement, J., Kubera, B., Eggeling, J., Rädel, C., Wagner, C., Park, S. Q., & Peters, A. (2018). Effects of blood glucose on delay discounting, food intake and counterregulation in lean and obese men. Psychoneuroendocrinology, 89, 177–184. https://doi.org/10.1016/j.psyneuen.2018.01.014
Testa, G., Camacho‐Barcia, L., Gómez‐Martínez, C., Mora‐Maltas, B., de la Torre, R., Pintó, X., Corella, D., Granero, R., Cuenca‐Royo, A., Jiménez‐Murcia, S., Babio, N., Fernández‐Carrión, R., Esteve‐Luque, V., Forcano, L., Ni, J., Malcampo, M., De Las Heras‐Delgado, S., Fitó, M., Salas‐Salvadó, J., & Fernández‐Aranda, F. (2022). Impulsive personality traits predicted weight loss in individuals with type 2 diabetes after 3 years of lifestyle interventions. Journal of Clinical Medicine, 11(12), 3476. https://doi.org/10.3390/jcm11123476
Salas‐Salvadó, J., Díaz‐López, A., Ruiz‐Canela, M., Basora, J., Fitó, M., Corella, D., Serra‐Majem, L., Wärnberg, J., Romaguera, D., Estruch, R., Vidal, J., Martínez, J. A., Arós, F., Vázquez, C., Ros, E., Vioque, J., López‐Miranda, J., Bueno‐Cavanillas, A., Tur, J. A., … PREDIMED‐Plus investigators. (2019). Effect of a lifestyle intervention program with energy‐restricted Mediterranean diet and exercise on weight loss and cardiovascular risk factors: One‐year results of the PREDIMED‐Plus Trial. Diabetes Care, 42(5), 777–788. https://doi.org/10.2337/dc18‐0836
Martínez‐González, M. A., Buil‐Cosiales, P., Corella, D., Bulló, M., Fitó, M., Vioque, J., Romaguera, D., Martínez, J. A., Wärnberg, J., López‐Miranda, J., Estruch, R., Bueno‐Cavanillas, A., Arós, F., Tur, J. A., Tinahones, F., Serra‐Majem, L., Martín, V., Lapetra, J., Vázquez, C., … Salas‐Salvadó, J. (2019). Cohort Profile: Design and methods of the PREDIMED‐Plus randomized trial. International Journal of Epidemiology, 48(2), 387–388. https://doi.org/10.1093/ije/dyy225
Alberti, K. G., Eckel, R. H., Grundy, S. M., Zimmet, P. Z., Cleeman, J. I., Donato, K. A., Fruchart, J. C., James, W. P., Loria, C. M., & Smith, S. C., jr. (2009). Harmonizing the metabolic syndrome: A joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation, 120(16), 1640–1645. https://doi.org/10.1161/CIRCULATIONAHA.109.192644
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985). Homeostasis model assessment: Insulin resistance and beta‐cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 28(7), 412–419. https://doi.org/10.1007/BF00280883
American Diabetes Association Professional Practice Committee. (2022). 6. Glycemic Targets: Standards of Medical Care in Diabetes‐2022. Diabetes Care, 45(Suppl 1), S83–S96. https://doi.org/10.2337/dc22‐S006
Molina, L., Sarmiento, M., Peñafiel, J., Donaire, D., Garcia‐Aymerich, J., Gomez, M., Ble, M., Ruiz, S., Frances, A., Schröder, H., Marrugat, J., & Elosua, R. (2017). Validation of the Regicor Short Physical Activity Questionnaire for the adult population. PLoS ONE, 12(1), e0168148. https://doi.org/10.1371/journal.pone.0168148
Schröder, H., Zomeño, M. D., Martínez‐González, M. A., Salas‐Salvadó, J., Corella, D., Vioque, J., Romaguera, D., Martínez, J. A., Tinahones, F. J., Miranda, J. L., Estruch, R., Bueno‐Cavanillas, A., Alonso Gómez, A. M., Tur, J. A., Warnberg, J., Serra‐Majem, L., Martín, V., Vázquez, C., Lapetra, J., … Castañer, O. (2021). Validity of the energy‐restricted Mediterranean Diet Adherence Screener. Clinical Nutrition, 40(8), 4971–4979. https://doi.org/10.1016/j.clnu.2021.06.030
Beck, A. T., Ward, C. H., Mendelson, M., Mock, J., & Erbaugh, J. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561–571. https://doi.org/10.1001/archpsyc.1961.01710120031004
Lynam, D. R., Smith, G. T., Whiteside, S. P., & Cyders, M. A. (2006). The UPPS‐P: Assessing five personality pathways to impulsive behavior. Purdue University.
Verdejo‐García, A., Lozano, O., Moya, M., Alcázar, M. A., & Pérez‐García, M. (2010). Psychometric properties of a Spanish version of the UPPS‐P impulsive behavior scale: Reliability, validity and association with trait and cognitive impulsivity. Journal of Personality Assessment, 92(1), 70–77. https://doi.org/10.1080/00223890903382369
Conners, C. K., Sitarenios, G., & Ayearst, L. E. (2018). Conners’ Continuous Performance Test Third Edition. In J. S. Kreutzer, J. DeLuca, & B. Caplan (Eds.), Encyclopedia of Clinical Neuropsychology (pp. 929–933). Springer. https://doi.org/10.1007/978‐3‐319‐57111‐9_1535
Bechara, A., Damasio, H., Tranel, D., & Damasio, A. R. (1997). Deciding advantageously before knowing the advantageous strategy. Science, 275(5304), 1293–1295. https://doi.org/10.1126/science.275.5304.1293
Golden, C. (2001). Manual STROOP‐Test de Colores y Palabras (3rd ed.). TEA Ediciones.
Rawlings, A. M., Sharrett, A. R., Schneider, A. L., Coresh, J., Albert, M., Couper, D., Griswold, M., Gottesman, R. F., Wagenknecht, L. E., Windham, B. G., & Selvin, E. (2014). Diabetes in midlife and cognitive change over 20 years: A cohort study. Annals of Internal Medicine, 161(11), 785–793. https://doi.org/10.7326/M14‐0737
Tuligenga, R. H., Dugravot, A., Tabák, A. G., Elbaz, A., Brunner, E. J., Kivimäki, M., & Singh‐Manoux, A. (2014). Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: A post‐hoc analysis of the Whitehall II cohort study. Lancet Diabetes & Endocrinology, 2(3), 228–235. https://doi.org/10.1016/S2213‐8587(13)70192‐X
Sharma, L., Markon, K. E., & Clark, L. A. (2014). Toward a theory of distinct types of “impulsive” behaviors: A meta‐analysis of self‐report and behavioral measures. Psychological Bulletin, 140(2), 374–408. https://doi.org/10.1037/a0034418
Creswell, K. G., Wright, A. G. C., Flory, J. D., Skrzynski, C. J., & Manuck, S. B. (2019). Multidimensional assessment of impulsivity‐related measures in relation to externalizing behaviors. Psychological Medicine, 49(10), 1678–1690. https://doi.org/10.1017/S0033291718002295
Laron, Z. (2009). Insulin and the brain. Archives of Physiology and Biochemistry, 115(2), 112–116. https://doi.org/10.1080/13813450902949012
Edwin Thanarajah, S., Iglesias, S., Kuzmanovic, B., Rigoux, L., Stephan, K. E., Brüning, J. C., & Tittgemeyer, M. (2019). Modulation of midbrain neurocircuitry by intranasal insulin. Neuroimage, 194, 120–127. https://doi.org/10.1016/j.neuroimage.2019.03.050
Heni, M., Kullmann, S., Ketterer, C., Guthoff, M., Linder, K., Wagner, R., Stingl, K. T., Veit, R., Staiger, H., Häring, H. U., Preissl, H., & Fritsche, A. (2012). Nasal insulin changes peripheral insulin sensitivity simultaneously with altered activity in homeostatic and reward‐related human brain regions. Diabetologia, 55(6), 1773–1782. https://doi.org/10.1007/s00125‐012‐2528‐y
Scherer, T., Sakamoto, K., & Buettner, C. (2021). Brain insulin signalling in metabolic homeostasis and disease. Nature Reviews Endocrinology, 17(8), 468–483. https://doi.org/10.1038/s41574‐021‐00498‐x
Levine, J. E. (2000). The hypothalamus as a major integrating center. In P. M. Conn, & M. E. Freeman (Eds.), Neuroendocrinology in physiology and medicine (pp. 75–93). Humana Press. https://doi.org/10.1007/978‐1‐59259‐707‐9_5
Eisenlohr‐Moul, T. A., & Owens, S. A. (2020). Hormones and personality. In V. Zeigler‐Hill, & T. K. Shackelford (Eds.), Encyclopedia of personality and individual differences (pp. 2010–2032). Springer. https://doi.org/10.1007/978‐3‐319‐24612‐3_762
Erlanger, D. M., Kutner, K. C., & Jacobs, A. R. (1999). Hormones and cognition: Current concepts and issues in neuropsychology. Neuropsychology Review, 9(4), 175–207. https://doi.org/10.1023/a:1021634622577
Noble, E. E., Wang, Z., Liu, C. M., Davis, E. A., Suarez, A. N., Stein, L. M., Tsan, L., Terrill, S. J., Hsu, T. M., Jung, A. H., Raycraft, L. M., Hahn, J. D., Darvas, M., Cortella, A. M., Schier, L. A., Johnson, A. W., Hayes, M. R., Holschneider, D. P., & Kanoski, S. E. (2019). Hypothalamus‐hippocampus circuitry regulates impulsivity via melanin‐concentrating hormone. Nature Communications, 10(1), 4923. https://doi.org/10.1038/s41467‐019‐12895‐y
Pereira‐da‐Silva, M., De Souza, C. T., Gasparetti, A. L., Saad, M. J., & Velloso, L. A. (2005). Melanin‐concentrating hormone induces insulin resistance through a mechanism independent of body weight gain. Journal of Endocrinology, 186(1), 193–201. https://doi.org/10.1677/joe.1.06111
Hirschberg, P. R., Sarkar, P., Teegala, S. B., & Routh, V. H. (2020). Ventromedial hypothalamus glucose‐inhibited neurones: A role in glucose and energy homeostasis? Journal of Neuroendocrinology, 32(1), e12773. https://doi.org/10.1111/jne.12773
Gómez‐Martínez, C., Babio, N., Júlvez, J., Becerra‐Tomás, N., Martínez‐González, M. Á., Corella, D., Castañer, O., Romaguera, D., Vioque, J., Alonso‐Gómez, Á. M., Wärnberg, J., Martínez, J. A., Serra‐Majem, L., Estruch, R., Tinahones, F. J., Lapetra, J., Pintó, X., Tur, J. A., López‐Miranda, J., … Salas‐Salvadó, J. (2021). Glycemic dysregulations are associated with worsening cognitive function in older participants at high risk of cardiovascular disease: Two‐year follow‐up in the PREDIMED‐Plus study. Frontiers in Endocrinology, 12, 754347. https://doi.org/10.3389/fendo.2021.754347
Monnier, L., Mas, E., Ginet, C., Michel, F., Villon, L., Cristol, J. P., & Colette, C. (2006). Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes. JAMA, 295(14), 1681–1687. https://doi.org/10.1001/jama.295.14.1681
Ceriello, A., Esposito, K., Piconi, L., Ihnat, M. A., Thorpe, J. E., Testa, R., Boemi, M., & Giugliano, D. (2008). Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients. Diabetes, 57(5), 1349–1354. https://doi.org/10.2337/db08‐0063
Sun, D. M., Ma, Y., Sun, Z. B., Xie, L., Huang, J. Z., Chen, W. S., Duan, S. X., Lin, Z. R., Guo, R. W., Le, H. B., Xu, W. C., & Ma, S. H. (2017). Decision‐making in primary onset middle‐age type 2 diabetes mellitus: A BOLD‐fMRI study. Scientific Reports, 7(1), 10246. https://doi.org/10.1038/s41598‐017‐10228‐x
Norrie, J. (2023). The importance of long‐term follow‐up in clinical trials. Lancet Global Health, 11(7), e995–e996. https://doi.org/10.1016/S2214‐109X(23)00244‐9
Konieczna, J., Ruiz‐Canela, M., Galmes‐Panades, A. M., Abete, I., Babio, N., Fiol, M., Martín‐Sánchez, V., Estruch, R., Vidal, J., Buil‐Cosiales, P., García‐Gavilán, J. F., Moñino, M., Marcos‐Delgado, A., Casas, R., Olbeyra, R., Fitó, M., Hu, F. B., Martínez‐Gonzalez, M. Á., Martínez, J. A., … Salas‐Salvadó, J. (2023). An energy‐reduced Mediterranean diet, physical activity, and body composition: An interim subgroup analysis of the PREDIMED‐Plus randomized clinical trial. JAMA Network Open, 6(10), e2337994. https://doi.org/10.1001/jamanetworkopen.2023.37994
Levine, G. N., Cohen, B. E., Commodore‐Mensah, Y., Fleury, J., Huffman, J. C., Khalid, U., Labarthe, D. R., Lavretsky, H., Michos, E. D., Spatz, E. S., & Kubzansky, L. D. (2021). Psychological health, well‐being, and the mind‐heart‐body connection: A scientific statement from the American Heart Association. Circulation, 143(10), e763–e783. https://doi.org/10.1161/CIR.0000000000000947