Zinc-finger protein ZFP488 regulates the timing of oligodendrocyte myelination and remyelination.
Journal
The Journal of neuroscience : the official journal of the Society for Neuroscience
ISSN: 1529-2401
Titre abrégé: J Neurosci
Pays: United States
ID NLM: 8102140
Informations de publication
Date de publication:
16 Aug 2024
16 Aug 2024
Historique:
received:
20
01
2024
revised:
28
07
2024
accepted:
07
08
2024
medline:
17
8
2024
pubmed:
17
8
2024
entrez:
16
8
2024
Statut:
aheadofprint
Résumé
Oligodendrocyte myelination and remyelination after injury are intricately regulated by various intrinsic and extrinsic factors, including transcriptional regulators. Among these, the zinc-finger protein ZFP488 is an oligodendrocyte-enriched transcriptional regulator that promotes oligodendrocyte differentiation in the developing neural tube and in oligodendroglial cell lines. However, the specific in vivo genetic requirements for ZFP488 during oligodendrocyte development and remyelination have not been defined. To address this gap, we generated a lineage-traceable
Identifiants
pubmed: 39151953
pii: JNEUROSCI.0141-24.2024
doi: 10.1523/JNEUROSCI.0141-24.2024
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2024 the authors.