Thrombotic Microangiopathy in Pregnancy: Current Understanding and Management Strategies.
complement
microangiopathic hemolytic anemia
pregnancy
thrombocytopenia
thrombotic microangiopathy
Journal
Kidney international reports
ISSN: 2468-0249
Titre abrégé: Kidney Int Rep
Pays: United States
ID NLM: 101684752
Informations de publication
Date de publication:
Aug 2024
Aug 2024
Historique:
received:
27
10
2023
revised:
09
05
2024
accepted:
13
05
2024
medline:
19
8
2024
pubmed:
19
8
2024
entrez:
19
8
2024
Statut:
epublish
Résumé
Thrombotic microangiopathy (TMA) represents a heterogeneous group of disorders characterized by microvascular thrombosis and end-organ damage. Pregnancy-associated thrombotic microangiopathy (p-TMA) has emerged as a distinct clinical entity with unique diagnostic challenges. Identifying the specific form of p-TMA is critical for appropriate and timely management. This review offers a comprehensive overview of the various forms of thrombotic microangiopathies associated with pregnancy, highlighting our current understanding of their pathophysiology and the evolving landscape of diagnosis and treatment for each.
Identifiants
pubmed: 39156177
doi: 10.1016/j.ekir.2024.05.016
pii: S2468-0249(24)01739-X
pmc: PMC11328568
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
2353-2371Informations de copyright
© 2024 International Society of Nephrology. Published by Elsevier Inc.