Treatment randomisation at animal or pen level? : Statistical analysis should follow the randomisation pattern!
Mycoplasma hyopneumoniae
Randomisation
clustered-randomised trials
repeated measurements
replication
Journal
Laboratory animals
ISSN: 1758-1117
Titre abrégé: Lab Anim
Pays: England
ID NLM: 0112725
Informations de publication
Date de publication:
19 Aug 2024
19 Aug 2024
Historique:
medline:
19
8
2024
pubmed:
19
8
2024
entrez:
19
8
2024
Statut:
aheadofprint
Résumé
Random treatment assignment is essential in demonstrating a causal relationship between a treatment and the outcome of interest. Randomisation ensures that animals assigned to different treatment groups do not differ from each other systematically, except for the randomly assigned treatment. The randomisation pattern should also dictate the statistical analysis.
Identifiants
pubmed: 39157977
doi: 10.1177/00236772241247274
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
236772241247274Déclaration de conflit d'intérêts
Declaration of conflicting interestsThe authors have no conflicts of interest to declare.