The HOPE cohort: cohort profile and evaluation of selection bias.

Cohort profile Edinburgh postnatal depression scale Postpartum depression Selection

Journal

European journal of epidemiology
ISSN: 1573-7284
Titre abrégé: Eur J Epidemiol
Pays: Netherlands
ID NLM: 8508062

Informations de publication

Date de publication:
19 Aug 2024
Historique:
received: 05 01 2024
accepted: 07 08 2024
medline: 19 8 2024
pubmed: 19 8 2024
entrez: 19 8 2024
Statut: aheadofprint

Résumé

The HOPE cohort is a Danish nationwide cohort with ongoing follow-up, holding information on postpartum depression (PPD) symptoms and diagnoses on 170,218 childbirths (142,795 unique mothers). These data have been linked with extensive register data on health and socioeconomic information on the mothers, their partners, parents, and children. This cohort profile aimed to provide an overview of the data collection and content, describe characteristics, and evaluate potential selection bias. PPD screenings, using the Edinburgh Postnatal Depression Scale, were collected from 67 of the 98 Danish municipalities, covering the period January 2015 to December 2021. This data was linked with register data on PPD diagnoses (identified through medication prescriptions and hospital contacts) as well as background information. Cohort characteristics were compared to the source population, defined as all childbirths by women residing in Denmark during the same period (452,207 childbirths). Potential selection bias was evaluated by comparing odds ratios of five well-established associations between the cohort and the source population. The HOPE cohort holds information on 170,218 childbirths (38% of the source population) involving 142,795 unique mothers. The HOPE cohort only differed slightly from the source population on most characteristics examined, but larger differences were observed on specific characteristics with an underrepresentation of the youngest and oldest age groups, women with more than three children or twins/triplets, and women born outside Denmark. Similar associations were identified across the two populations within the five well-established associations. There was no indication of selection bias on the five examined associations, and the HOPE cohort is representative of the source population on important perinatal characteristics.

Identifiants

pubmed: 39158818
doi: 10.1007/s10654-024-01150-4
pii: 10.1007/s10654-024-01150-4
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2024. The Author(s).

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Auteurs

Mette-Marie Zacher Kjeldsen (MM)

NCRR-National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark. Mmzk.ncrr@au.dk.
Department of Public Health, Aarhus University, Aarhus, Denmark. Mmzk.ncrr@au.dk.
CIRRAU - Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark. Mmzk.ncrr@au.dk.

Merete Lund Mægbæk (ML)

NCRR-National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
CIRRAU - Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.

Xiaoqin Liu (X)

NCRR-National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
CIRRAU - Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.

Malene Galle Madsen (MG)

NCRR-National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.

Mette Bliddal (M)

Research Unit OPEN, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.

Sofie Egsgaard (S)

Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Child and Adolescent Psychiatric Unit, Region of Southern Denmark, Odense, Denmark.

Kathrine Bang Madsen (K)

NCRR-National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
CIRRAU - Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.

Trine Munk-Olsen (T)

NCRR-National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark.
Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Child and Adolescent Psychiatric Unit, Region of Southern Denmark, Odense, Denmark.

Classifications MeSH