Prognostic value of cardiopulmonary exercise test in children with congenital heart defects.


Journal

Open heart
ISSN: 2053-3624
Titre abrégé: Open Heart
Pays: England
ID NLM: 101631219

Informations de publication

Date de publication:
19 Aug 2024
Historique:
received: 02 07 2024
accepted: 12 07 2024
medline: 20 8 2024
pubmed: 20 8 2024
entrez: 19 8 2024
Statut: epublish

Résumé

Cardiopulmonary exercise testing (CPET) has an important prognostic value in adults with different congenital heart defects (CHDs) and is a useful tool for risk stratification and clinical decision-making. In this retrospective study, we studied the prognostic value of CPET in paediatric patients with CHD. 411 CPET performed by paediatric patients with different CHDs were evaluated in this retrospective study. Medical records were reviewed to determine the presence of cardiac events. Participants were classified using the 2018 AHA/ACC guideline for the management of adults with CHD that combines anatomical complexity and current physiological stage. 411 patients with a median age at test of 12 years, 51 patients with simple CHD, 170 patients with moderate complexity CHD and 190 with high complexity CHD underwent CPET. Overall, CPET parameters were lower than the reference values (%predicted VO Reduced exercise capacity at young age is related to a higher probability of future cardiovascular events in paediatric patients with CHD. Submaximal exercise variables can be used instead when maximal exercise cannot be achieved.

Sections du résumé

BACKGROUND BACKGROUND
Cardiopulmonary exercise testing (CPET) has an important prognostic value in adults with different congenital heart defects (CHDs) and is a useful tool for risk stratification and clinical decision-making. In this retrospective study, we studied the prognostic value of CPET in paediatric patients with CHD.
METHODS METHODS
411 CPET performed by paediatric patients with different CHDs were evaluated in this retrospective study. Medical records were reviewed to determine the presence of cardiac events. Participants were classified using the 2018 AHA/ACC guideline for the management of adults with CHD that combines anatomical complexity and current physiological stage.
RESULTS RESULTS
411 patients with a median age at test of 12 years, 51 patients with simple CHD, 170 patients with moderate complexity CHD and 190 with high complexity CHD underwent CPET. Overall, CPET parameters were lower than the reference values (%predicted VO
CONCLUSION CONCLUSIONS
Reduced exercise capacity at young age is related to a higher probability of future cardiovascular events in paediatric patients with CHD. Submaximal exercise variables can be used instead when maximal exercise cannot be achieved.

Identifiants

pubmed: 39160087
pii: openhrt-2024-002820
doi: 10.1136/openhrt-2024-002820
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Covadonga Terol (C)

Department of Paediatrics, Division of Paediatric Cardiology, LUMC, Leiden, The Netherlands.

Juliette Hagen (J)

Department of Paediatrics, Division of Paediatric Cardiology, LUMC, Leiden, The Netherlands.

Lukas Rammeloo (L)

Department of Paediatrics, Division of Paediatric Cardiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands.

Irene M Kuipers (IM)

Department of Paediatrics, Division of Paediatric Cardiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands.

Nicolaas A Blom (NA)

Department of Paediatrics, Division of Paediatric Cardiology, LUMC, Leiden, The Netherlands n.a.blom@amsterdamumc.nl.
Department of Paediatrics, Division of Paediatric Cardiology, Amsterdam UMC Locatie AMC, Amsterdam, The Netherlands.

Arend Dj Ten Harkel (AD)

Department of Paediatrics, Division of Paediatric Cardiology, LUMC, Leiden, The Netherlands.

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