COVID-19 throughout pandemic waves and virus variants: a real-life experience in an Italian hospital.

Covid-19 SARS-CoV-2 pandemic waves remdesivir vaccine virus variants

Journal

Journal of chemotherapy (Florence, Italy)
ISSN: 1973-9478
Titre abrégé: J Chemother
Pays: England
ID NLM: 8907348

Informations de publication

Date de publication:
19 Aug 2024
Historique:
medline: 20 8 2024
pubmed: 20 8 2024
entrez: 20 8 2024
Statut: aheadofprint

Résumé

New therapies and vaccines changed the management of COVID-19. The aim of this retrospective study was to describe characteristics, in-hospital mortality and its predictors in patients with moderate/severe COVID-19, considering the 4 different pandemic waves and viral variants' prevalence from February 2020 to January 2022. Among 1135 patients included, 873 (77%) had at least one comorbidity, 177 (16%) were immunocompromised. From waves 1 to 4, patients with severe respiratory failure and ICU admission decreased over time (

Identifiants

DOI: 10.1080/1120009X.2024.2384321 PMID: 39161053
pubmed: 39161053
doi: 10.1080/1120009X.2024.2384321
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-9

Auteurs

Silvia Dettori (S)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Giorgia Brucci (G)

Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Federica Portunato (F)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Marta Ponzano (M)

Section of Biostatistics, Department of Health Sciences, University of Genoa, Genoa, Italy.

Laura Magnasco (L)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Michele Mirabella (M)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Federica Magnè (F)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Emanuele Delfino (E)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Elisa Balletto (E)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Chiara Sepulcri (C)

Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Antonio Vena (A)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Daniele Roberto Giacobbe (DR)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Cristina Marelli (C)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Lorenzo Ball (L)

Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.

Malgorzata Mikulska (M)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Antonio Di Biagio (A)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Bianca Bruzzone (B)

Hygiene Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Alessio Signori (A)

Section of Biostatistics, Department of Health Sciences, University of Genoa, Genoa, Italy.
ORCID: 0000-0001-6289-9144

Sara Mora (S)

Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Genoa, Italy.

Mauro Giacomini (M)

Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Genoa, Italy.

Chiara Dentone (C)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.

Matteo Bassetti (M)

Infectious Diseases Unit, IRCCS Ospedale Policlinico San Martino, University of Genoa, Genoa, Italy.
Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.

Classifications MeSH