Zebrafish

SVCV antiviral response innate immunity mavs phd1 zebrafish

Journal

Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724

Informations de publication

Date de publication:
20 Aug 2024
Historique:
medline: 20 8 2024
pubmed: 20 8 2024
entrez: 20 8 2024
Statut: aheadofprint

Résumé

PHD1 is a member of the prolyl hydroxylase domain protein (PHD1-4) family, which plays a prominent role in the post-translational modification of its target proteins by hydroxylating proline residues. The best-characterized targets of PHD1 are hypoxia-inducible factor α (HIF-1α and HIF-2α), two master regulators of the hypoxia signaling pathway. In this study, we show that zebrafish phd1 positively regulates mavs-mediated antiviral innate immunity. Overexpression of

Identifiants

DOI: 10.1128/jvi.01038-24 PMID: 39162481
pubmed: 39162481
doi: 10.1128/jvi.01038-24
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0103824

Auteurs

Guangqing Yu (G)

College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.
ORCID: 0000-0003-4475-3613

Le Yuan (L)

Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.

Xiong Li (X)

Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.

Mingzhong Zuo (M)

College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.

Rui Wang (R)

Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.

Mengjuan Chen (M)

College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.

Yuqing Liu (Y)

College of Animal Science and Technology, Henan Agricultural University, Zhengzhou, People's Republic of China.

Xing Liu (X)

Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.
Hubei Hongshan Laboratory, Wuhan, People's Republic of China.
The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan, People's Republic of China.
ORCID: 0000-0001-9338-7440

Wuhan Xiao (W)

Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Chinese Academy of Sciences, Wuhan, People's Republic of China.
Hubei Hongshan Laboratory, Wuhan, People's Republic of China.
The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan, People's Republic of China.
University of Chinese Academy of Sciences, Beijing, People's Republic of China.
ORCID: 0000-0002-2978-0616

Classifications MeSH