Current understanding of infection of the Ventricles and its complications.

CNS devices Complications Ventriculitis diagnostic markers neurosurgical infections

Journal

Expert review of anti-infective therapy
ISSN: 1744-8336
Titre abrégé: Expert Rev Anti Infect Ther
Pays: England
ID NLM: 101181284

Informations de publication

Date de publication:
20 Aug 2024
Historique:
medline: 20 8 2024
pubmed: 20 8 2024
entrez: 20 8 2024
Statut: aheadofprint

Résumé

Ventriculitis, characterized by inflammation of the ventricles in the brain, frequently occurs as a complication of neurosurgical interventions such as the insertion of cerebrospinal fluid (CSF) shunts or external ventricular drains. It can also present as a community-acquired pathology, broadening its clinical significance and complicating diagnosis and treatment. This condition presents significant challenges, primarily due to its association with various medical devices and the predisposing conditions of patients which enhance infection risks. The review comprehensively explores the etiology, risk factors, diagnostic methodologies, and treatment options for ventriculitis. A thorough literature search was conducted, focusing on recent studies, meta-analyses, and clinical reports that discuss the incidence rates, the effectiveness of different management strategies, and the impact of device-related and community-acquired infections. Particular attention is given to the role of CSF drains and shunts, biofilms, and the prophylactic measures employed in clinical settings to mitigate infection risks. Despite advances in medical technology and infection control protocols, ventriculitis remains a severe complication in both neurosurgical and community settings. The review highlights the need for continued research into innovative diagnostic tools and more effective infection control strategies.

Identifiants

pubmed: 39163406
doi: 10.1080/14787210.2024.2395018
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Hazim Allos (H)

Department of Medicine, Section of Infectious Disease, McGovern Medical School, UTHealth Science Center, Houston, TX.

Rodrigo Hasbun (R)

Department of Medicine, Section of Infectious Disease, McGovern Medical School, UTHealth Science Center, Houston, TX.

Classifications MeSH