The effects of bolus isosorbide dinitrate on pulmonary hypertension with cardiopulmonary comorbidities.
Combined post- and pre-capillary pulmonary hypertension
Comorbidities
Diuretic
Isosorbide dinitrate
Preload
Journal
Heart and vessels
ISSN: 1615-2573
Titre abrégé: Heart Vessels
Pays: Japan
ID NLM: 8511258
Informations de publication
Date de publication:
21 Aug 2024
21 Aug 2024
Historique:
received:
31
05
2024
accepted:
14
08
2024
medline:
21
8
2024
pubmed:
21
8
2024
entrez:
20
8
2024
Statut:
aheadofprint
Résumé
Lowering mean pulmonary arterial pressure (mPAP) without reducing cardiac output is essential in treating pulmonary hypertension (PH). Isosorbide dinitrate (ISDN) potentially achieves this in post-capillary PH but can decrease cardiac output and blood pressure (BP), especially in pre-capillary PH. However, post-capillary PH and pre-capillary PH can overlap, and their clear discrimination is difficult. The aim of the study was to examine to what extent bolus ISDN injection reduces mPAP and BP, and changes mixed venous oxygen saturation (SvO
Identifiants
pubmed: 39164577
doi: 10.1007/s00380-024-02451-0
pii: 10.1007/s00380-024-02451-0
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024. Springer Nature Japan KK, part of Springer Nature.
Références
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