Renal protective roles of macrophage matrix metalloproteinase-12 in mice with obstructed kidneys.
bone marrow‐derived macrophage
fibrosis
inflammation
kidney disease
macrophage elastase
resolution‐promoting factor
Journal
International journal of experimental pathology
ISSN: 1365-2613
Titre abrégé: Int J Exp Pathol
Pays: England
ID NLM: 9014042
Informations de publication
Date de publication:
20 Aug 2024
20 Aug 2024
Historique:
revised:
05
08
2024
received:
11
04
2024
accepted:
05
08
2024
medline:
21
8
2024
pubmed:
21
8
2024
entrez:
21
8
2024
Statut:
aheadofprint
Résumé
Matrix metalloproteinase (MMP)-12 has been reported to have diverse functions, including regulation of immune reactions and anti-inflammatory effects, but the potential roles of MMP-12 in kidney injury have not been fully elucidated. This study aimed to determine whether MMP-12 contributes to tubulointerstitial injury in a unilateral ureteric obstruction (UUO) model. MMP-12-deficient (MMP-12
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© 2024 Company of the International Journal of Experimental Pathology (CIJEP).
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