Long-term effect of increasing water intake on repeated self-assessed health-related quality of life (HRQoL) in autosomal dominant polycystic kidney disease.

ADPKD CKD clinical trial polycystic kidney disease quality of life

Journal

Clinical kidney journal
ISSN: 2048-8505
Titre abrégé: Clin Kidney J
Pays: England
ID NLM: 101579321

Informations de publication

Date de publication:
Jul 2024
Historique:
received: 08 02 2024
medline: 21 8 2024
pubmed: 21 8 2024
entrez: 21 8 2024
Statut: epublish

Résumé

The aim of this study was to determine the long-term effect of increasing water intake in patients with autosomal dominant polycystic kidney disease (ADPKD) on longitudinal changes in health-related quality of life (HRQoL) in the setting of a clinical trial. Self-completed HRQoL (using the KDQoL-SF, v.1.3 questionnaire) was assessed annually in participants of a 3-year randomized controlled clinical trial ( Overall, 96% and 81.8% of participants ( HRQoL scores remained stable over a 3 year period, and were not adversely affected by the intervention to increase water intake. Future studies should evaluate the clinical significance of the higher PCS in the increased water intake group.

Sections du résumé

Background UNASSIGNED
The aim of this study was to determine the long-term effect of increasing water intake in patients with autosomal dominant polycystic kidney disease (ADPKD) on longitudinal changes in health-related quality of life (HRQoL) in the setting of a clinical trial.
Methods UNASSIGNED
Self-completed HRQoL (using the KDQoL-SF, v.1.3 questionnaire) was assessed annually in participants of a 3-year randomized controlled clinical trial (
Results UNASSIGNED
Overall, 96% and 81.8% of participants (
Conclusion UNASSIGNED
HRQoL scores remained stable over a 3 year period, and were not adversely affected by the intervention to increase water intake. Future studies should evaluate the clinical significance of the higher PCS in the increased water intake group.

Identifiants

DOI: 10.1093/ckj/sfae159 PMID: 39165901 PMC: PMC11333960
pubmed: 39165901
doi: 10.1093/ckj/sfae159
pii: sfae159
pmc: PMC11333960
doi:

Types de publication

Journal Article

Langues

eng

Pagination

sfae159

Informations de copyright

© The Author(s) 2024. Published by Oxford University Press on behalf of the ERA.

Déclaration de conflit d'intérêts

G.R. reports research grants and travel sponsorship from Danone Research, Otsuka, and Sanofi. D.W.J. has received consultancy fees, research grants, speaker's honoraria, and travel sponsorships from Baxter Healthcare and Fresenius Medical Care, consultancy fees from Astra Zeneca, Bayer, and AWAK, speaker's honoraria from ONO and Boehringer Ingelheim & Lilly, and travel sponsorships from ONO and Amgen.

Auteurs

Gopala Rangan (G)

Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney, Australia.
Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia.

Margaret Allman-Farinelli (M)

School of Nursing, The University of Sydney, Sydney, NSW, Australia.

Neil Boudville (N)

Sir Charles Gairdner Hospital, Perth, Australia.
Medical School, University of Western Australia, Perth, Australia.

Mangalee Fernando (M)

Department of Renal Medicine, Prince of Wales Hospital, Sydney, NSW, Australia.

Imad Haloob (I)

Department of Renal Medicine, Bathurst Hospital, Bathurst, Australia.

David C H Harris (DCH)

Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney, Australia.
Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia.

Carmel M Hawley (CM)

Australasian Kidney Trials Network, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia.
Translational Research Institute, Brisbane, Australia.
Department of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Australia.

Karthik Kumar (K)

Gosford Nephrology, Gosford, Australia.

David W Johnson (DW)

Australasian Kidney Trials Network, University of Queensland at Princess Alexandra Hospital, Brisbane, Australia.
Translational Research Institute, Brisbane, Australia.
Department of Kidney and Transplant Services, Princess Alexandra Hospital, Brisbane, Australia.

Vincent W Lee (VW)

Centre for Transplant and Renal Research, Westmead Institute for Medical Research, The University of Sydney, Sydney, Australia.
Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia.

Jun Mai (J)

Department of Renal Medicine, Liverpool Hospital, Southwestern Sydney Local Health District, Sydney, NSW, Australia.

Anna Rangan (A)

School of Nursing, The University of Sydney, Sydney, NSW, Australia.
ORCID: 0000-0003-1815-844X

Simon D Roger (SD)

Renal Research, Gosford, Australia.

Priyanka Sagar (P)

Nepean Kidney Research Centre, Department of Renal Medicine, Nepean Hospital and Nepean Clinical School, The University of Sydney, Sydney, Australia.

Kamal Sud (K)

Nepean Kidney Research Centre, Department of Renal Medicine, Nepean Hospital and Nepean Clinical School, The University of Sydney, Sydney, Australia.

Vicente Torres (V)

Translational Polycystic Kidney Disease Center, Mayo Clinic, Rochester, USA.

Eswari Vilayur (E)

Department of Nephrology, John Hunter Hospital, Newcastle, Australia.

Classifications MeSH