Direct breastfeeding: Predictive factors and possible effects on neurodevelopment in very preterm infants.

Breastmilk Direct breastfeeding Neurodevelopment Preterm infant

Journal

Early human development
ISSN: 1872-6232
Titre abrégé: Early Hum Dev
Pays: Ireland
ID NLM: 7708381

Informations de publication

Date de publication:
14 Aug 2024
Historique:
received: 04 06 2024
revised: 09 08 2024
accepted: 10 08 2024
medline: 22 8 2024
pubmed: 22 8 2024
entrez: 21 8 2024
Statut: aheadofprint

Résumé

the importance of sucking milk directly at the mother's breast is often underestimated and many aspects of direct breastfeeding of very preterm infants are not investigated. The primary endpoint of the study was to identify maternal and infant clinical predictors of direct breastfeeding in a cohort of infants born at <32 weeks of gestation or weighing <1500 g. The secondary endpoint was to evaluate the possible effects of direct breastfeeding on infant neurodevelopment. Seventy-two infants born between July 2018 and December 2019 were divided into the subgroup that were directly breastfed (n = 42) and not directly breastfed (n = 30) at discharge. Maternal and infant characteristics were compared, and differences were analysed. Logistic regression analysis demonstrated that the percentage of maternal milk taken during hospitalization, maternal age, and weight (z-score) at discharge were positively correlated with the likelihood of direct breastfeeding at discharge. Direct breastfeeding was not correlated with the cognitive score at 24 months corrected age. Direct breastfeeding at discharge is more probable in infants of older mothers who receive more breastmilk and who experience greater weight gain. Direct breastfeeding is not correlated with the cognitive score at 24 months corrected age.

Sections du résumé

BACKGROUND BACKGROUND
the importance of sucking milk directly at the mother's breast is often underestimated and many aspects of direct breastfeeding of very preterm infants are not investigated.
AIM OBJECTIVE
The primary endpoint of the study was to identify maternal and infant clinical predictors of direct breastfeeding in a cohort of infants born at <32 weeks of gestation or weighing <1500 g. The secondary endpoint was to evaluate the possible effects of direct breastfeeding on infant neurodevelopment.
STUDY DESIGN METHODS
Seventy-two infants born between July 2018 and December 2019 were divided into the subgroup that were directly breastfed (n = 42) and not directly breastfed (n = 30) at discharge. Maternal and infant characteristics were compared, and differences were analysed.
RESULTS RESULTS
Logistic regression analysis demonstrated that the percentage of maternal milk taken during hospitalization, maternal age, and weight (z-score) at discharge were positively correlated with the likelihood of direct breastfeeding at discharge. Direct breastfeeding was not correlated with the cognitive score at 24 months corrected age.
CONCLUSIONS CONCLUSIONS
Direct breastfeeding at discharge is more probable in infants of older mothers who receive more breastmilk and who experience greater weight gain. Direct breastfeeding is not correlated with the cognitive score at 24 months corrected age.

Identifiants

pubmed: 39167914
pii: S0378-3782(24)00168-3
doi: 10.1016/j.earlhumdev.2024.106099
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

106099

Informations de copyright

Copyright © 2024. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Declaration of competing interest Authors declare no conflicts of interest relating to the work under submission.

Auteurs

Carlo Dani (C)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy; Department of Neurosciences, Psychology, Drug Research, and Child Health, University of Florence, Florence, Italy. Electronic address: cdani@unifi.It.

Caterina Coviello (C)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Martina Ciarcià (M)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Monica Fusco (M)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Clara Lunardi (C)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Giulia Remaschi (G)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Davide Sarcina (D)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Giovanni Sassudelli (G)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Simone Pratesi (S)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Silvia Perugi (S)

Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy.

Classifications MeSH