Long-term residence and efficacy of adenovirus-mimetic nanoparticles in renal target tissue.

In vivo disease model drug encapsulation intravital microscopy polymer nanoparticles renal targeting

Journal

Journal of drug targeting
ISSN: 1029-2330
Titre abrégé: J Drug Target
Pays: England
ID NLM: 9312476

Informations de publication

Date de publication:
22 Aug 2024
Historique:
medline: 22 8 2024
pubmed: 22 8 2024
entrez: 22 8 2024
Statut: aheadofprint

Résumé

A major shortcoming in the treatment of mesangial cell-associated diseases such as IgA nephropathy, diabetic nephropathy, or lupus nephritis, which frequently progress to end-stage renal disease, is poor drug availability in the glomerular mesangium. Drug delivery

Identifiants

DOI: 10.1080/1061186X.2024.2390628 PMID: 39171543
pubmed: 39171543
doi: 10.1080/1061186X.2024.2390628
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-13

Auteurs

Melanie Walter (M)

Department of Pharmaceutical Technology, University of Regensburg, Regensburg, Bavaria, Germany.

Hannah Weißbach (H)

Department of Internal Medicine III, Division of Nephrology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.

Florian Gembardt (F)

Department of Internal Medicine III, Division of Nephrology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.

Sagor Halder (S)

Department of Internal Medicine III, Division of Nephrology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.

Kathrin Schorr (K)

Department of Pharmaceutical Technology, University of Regensburg, Regensburg, Bavaria, Germany.

Daniel Fleischmann (D)

Department of Pharmaceutical Technology, University of Regensburg, Regensburg, Bavaria, Germany.

Vladimir Todorov (V)

Department of Internal Medicine III, Division of Nephrology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.
Department of Physiology and Pathophysiology, Center of Biomedical Education and Research (ZBAF), Faculty of Health - School of Medicine, Witten/Herdecke University, Witten, Germany.

Christian Hugo (C)

Department of Internal Medicine III, Division of Nephrology, University Hospital Carl Gustav Carus at the Technische Universität Dresden, Dresden, Germany.

Achim Goepferich (A)

Department of Pharmaceutical Technology, University of Regensburg, Regensburg, Bavaria, Germany.

Classifications MeSH