Prevalence of oral diseases in patients under palliative care: a systematic review and meta-analysis.
Mouth diseases
Oral manifestations
Palliative care
Terminal care
Journal
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
ISSN: 1433-7339
Titre abrégé: Support Care Cancer
Pays: Germany
ID NLM: 9302957
Informations de publication
Date de publication:
22 Aug 2024
22 Aug 2024
Historique:
received:
05
04
2024
accepted:
05
07
2024
medline:
22
8
2024
pubmed:
22
8
2024
entrez:
22
8
2024
Statut:
epublish
Résumé
Oral alterations are frequently observed in patients undergoing palliative care and are linked to the direct or indirect effects of the primary medical condition, comorbidities and medical management, leading to oral pain, impacting oral intake, and affecting quality of life. This systematic review aims to assess the prevalence of oral disease in palliative care patients. The protocol was registered at the PROSPERO database, and a systematic review of the literature was performed based on the PRISMA statement. A thorough evaluation of studies from five databases and gray literature was conducted. The risk of bias in each study was assessed using the Joanna Briggs Institute checklist for cross-sectional and case-control studies. A quantitative analysis was conducted on five studies using meta-analysis, and the degree of certainty in the evidence was determined using the GRADE tool. The sample consisted of 2,502 patients, with a slight male predominance (50.43%). The average age was 66.92 years. The prevalence of oral diseases among palliative care patients was as follows: caries 32% (95% CI, 0.11-0.56; I Dental intervention should take place as early as possible, ideally from the time of the patient's initial admission to palliative care, with regular monitoring of oral health. This approach can enhance the patient's comfort and quality of life and help prevent more severe complications in the future.
Identifiants
pubmed: 39172259
doi: 10.1007/s00520-024-08723-9
pii: 10.1007/s00520-024-08723-9
doi:
Types de publication
Journal Article
Systematic Review
Meta-Analysis
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
607Subventions
Organisme : Coordination for the Improvement of Higher Education Personnel
ID : 001
Organisme : Sao Paulo Research Foundation
ID : 2019/09692-9
Organisme : Sao Paulo Research Foundation
ID : 2019/09692-9
Organisme : Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
ID : 307604/2023-3
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
World Health Organization (2002) National cancer control programmes: policies and managerial guidelines. https://www.who.int/publications/i/item/national-cancer-control-programmes Accessed August 28, 2023
O'Neill B, Fallon M (1997) ABC of palliative care. Principles of palliative care and pain control. BMJ 315(7111):801–4. https://doi.org/10.1136/bmj.315.7111.801
Rome RB, Luminais HH, Bourgeois DA, Blais CM (2011) The role of palliative care at the end of life. Ochsner J Winter 11(4):348–352
Agarwal R, Epstein AS (2017) The Role of Palliative Care in Oncology. Semin Intervent Radiol 34(4):307–312. https://doi.org/10.1055/s-0037-1608702
doi: 10.1055/s-0037-1608702
pubmed: 29249853
pmcid: 5730447
Chen X, D’Souza V, Thomsen TA, Gilbertson-White S, Madiloggovit J, Pendleton C, Munjal A, Xianjin X (2021) Oral health in adult patients receiving palliative care: a Mixed Method Study. Am J Hosp Palliat Med 38(12):1516–1525. https://doi.org/10.1177/10499091211007449
doi: 10.1177/10499091211007449
Saini R, Pp M, Shete S et al (2009) Dental expression and role in palliative treatment. Indian J Palliat Care 15(1):26–29. https://doi.org/10.4103/0973-1075.53508
doi: 10.4103/0973-1075.53508
pubmed: 20606852
pmcid: 2886216
Kvalheim SF, Marthinussen IMC, Berg E, Strand GV (2022) Dry mouth in the seriously ill and dying. Tidsskr Nor Laegeforen 142(3). https://doi.org/10.4045/tidsskr.21.0232
World Health Organization (2018) Integrating palliative care and symptom relief into primary health care: a WHO guide for planners, implementers and managers. https://iris.who.int/handle/10665/274559 . Accessed 28 Aug 2023
Silva ARP, Bodanezi AV, Chrun ES, Lisboa ML, de Camargo AR, Munhoz EA (2023) Palliative oral care in terminal cancer patients: Integrated review. World J Clin Cases 11(13):2966–2980. https://doi.org/10.12998/wjcc.v11.i13.2966
doi: 10.12998/wjcc.v11.i13.2966
pubmed: 37215429
pmcid: 10198072
Meneguin S, Matos TDS, Ferreira MLDSM (2018) Perception of cancer patients in palliative care about quality of life. Rev Bras Enferm 71(4):1998–2004. https://doi.org/10.1590/0034-7167-2017-0360
doi: 10.1590/0034-7167-2017-0360
pubmed: 30156689
Funkhouser WK (2009) Pathology: The Clinical Description of Human Disease. Molecular Pathology. pp 197–207. https://doi.org/10.1016/B978-0-12-374419-7.00011-1
Kottow MH (1980) A medical definition of disease. Med Hypotheses 6(2):209–213. https://doi.org/10.1016/0306-9877(80)90085-7
doi: 10.1016/0306-9877(80)90085-7
pubmed: 7393019
Eisenberg L (1977) Disease and illness. Distinctions between professional and popular ideas of sickness. Cult Med Psychiatry 1(1):9–23. https://doi.org/10.1007/BF00114808
https://www.nature.com/subjects/oral-manifestations . Accessed June 15, 2023
Porter S, Mercadente V, Fedele S (2018) Oral manifestations of systemic disease. BDJ Team 5:18012. https://doi.org/10.1038/bdjteam.2018.12
doi: 10.1038/bdjteam.2018.12
Venkatasalu MR, Murang ZR, Ramasamy DTR, Dhaliwal JS (2020) Oral health problems among palliative and terminally ill patients: an integrated systematic review. BMC Oral Health 20(1):79. https://doi.org/10.1186/s12903-020-01075-w
doi: 10.1186/s12903-020-01075-w
pubmed: 32188452
pmcid: 7079519
Page MJ, McKenzie JE, Bossuyt PM et al (2021) The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ 372:n71. https://doi.org/10.1136/bmj.n71
doi: 10.1136/bmj.n71
pubmed: 33782057
pmcid: 8005924
Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid A (2016) Rayyan-a web and mobile app for systematic reviews. Syst Rev 5(1):210. https://doi.org/10.1186/s13643-016-0384-4
doi: 10.1186/s13643-016-0384-4
pubmed: 27919275
pmcid: 5139140
Moola S, Munn Z, Sears K, Sfetcu R, Currie M, Lisy K, Tufanaru C, Qureshi R, Mattis P, Mu P (2015) Conducting systematic reviews of association (etiology): The Joanna Briggs Institute’s approach. Int J Evid Based Health 13(3):163–169. https://doi.org/10.1097/XEB.0000000000000064
doi: 10.1097/XEB.0000000000000064
Migliavaca CB, Stein C, Colpani V, Barker TH, Ziegelmann PK, Munn Z, Falavigna M (2022) Meta-analysis of prevalence: I
doi: 10.1002/jrsm.1547
pubmed: 35088937
Balshem H, Helfand M, Schünemann HJ et al (2011) GRADE guidelines: 3 Rating the quality of evidence. J Clin Epidemiol 64(4):401–406. https://doi.org/10.1016/j.jclinepi.2010.07.015
doi: 10.1016/j.jclinepi.2010.07.015
pubmed: 21208779
Burge FI (1993) Dehydration symptoms of palliative care cancer patients. J Pain Symptom Manage 8(7):454–464. https://doi.org/10.1016/0885-3924(93)90188-2
doi: 10.1016/0885-3924(93)90188-2
pubmed: 7525778
Fischer DJ, Epstein JB, Yao Y, Wilkie DJ (2014) Oral health conditions affect functional and social activities of terminally ill cancer patients. Support Care Cancer 22(3):803–810. https://doi.org/10.1007/s00520-013-2037-7
doi: 10.1007/s00520-013-2037-7
pubmed: 24232310
pmcid: 3962694
da Fonseca Orcina B, Jaccottet CMG, Savian MCB (2021) Prevalence of Oral Manifestations in Cancer Patients Enrolled in a Home Care Program in the City of Pelotas-RS. Revista Brasileira de Cancerologia 67(2):081184. https://doi.org/10.32635/2176-9745.RBC.2021v67n2.1184
doi: 10.32635/2176-9745.RBC.2021v67n2.1184
Davies A, Buchanan A, Todd J, Gregory A, Batsari KM (2021) Oral symptoms in patients with advanced cancer: an observational study using a novel oral symptom assessment scale. Support Care Cancer 29(8):4357–4364. https://doi.org/10.1007/s00520-020-05903-1
doi: 10.1007/s00520-020-05903-1
pubmed: 33416995
Fleming M, Craigs CL, Bennett MI (2020) Palliative care assessment of dry mouth: what matters most to patients with advanced disease? Support Care Cancer 28(3):1121–1129. https://doi.org/10.1007/s00520-019-04908-9
doi: 10.1007/s00520-019-04908-9
pubmed: 31201546
Maltoni M, Pirovano M, Scarpi E, Marinari M, Indelli M, Arnoldi E, Amadori D (1995) Prediction of survival of patients terminally III with cancer. Results of an Italian prospective multicentric study. Cancer 75(10):2613–2622. https://doi.org/10.1002/1097-0142(19950515)75:10%3c2613::aid-cncr2820751032%3e3.0.co;2-1
doi: 10.1002/1097-0142(19950515)75:10<2613::aid-cncr2820751032>3.0.co;2-1
pubmed: 7537625
Mercadante S, Aielli F, Adile C, Ferrera P, Valle A, Fusco F, Porzio G (2015) Prevalence of oral mucositis, dry mouth, and dysphagia in advanced cancer patients. Support Care Cancer 23(11):3249–3255. https://doi.org/10.1007/s00520-015-2720-y
doi: 10.1007/s00520-015-2720-y
pubmed: 25832897
Wilberg P, Hjermstad MJ, Ottesen S, Herlofson BB (2012) Oral health is an important issue in end-of-life cancer care. Support Care Cancer 20(12):3115–3122. https://doi.org/10.1007/s00520-012-1441-8
doi: 10.1007/s00520-012-1441-8
pubmed: 22434497
Magnani C, Mastroianni C, Giannarelli D, Stefanelli MC, Di Cienzo V, Valerioti T, Casale G (2019) Oral hygiene care in patients with advanced disease: an essential measure to improve oral cavity conditions and symptom management. Am J Hosp Palliat Care 36(9):815–819. https://doi.org/10.1177/1049909119829411
doi: 10.1177/1049909119829411
pubmed: 30754984
Nakajima N (2017) Characteristics of oral problems and effects of oral care in terminally ill patients with cancer. American Journal of Hospice and Palliative Medicine® 34(5):430–434. https://doi.org/10.1177/1049909116633063
Amran NAH, Rahman HA, Awang AMZBH, Murang ZR, Nara A, Teo SP, Dhaliwal JS (2022) Assessment of oral health problems and oral hygiene practices among palliative care patients using a new tool: A pilot study. Palliative Medicine in Practice 16(1):49–58. https://doi.org/10.5603/PMPI.2021.0030
doi: 10.5603/PMPI.2021.0030
Matsuo K, Watanabe R, Kanamori D et al (2016) Associations between oral complications and days to death in palliative care patients. Support Care Cancer 24(1):157–161. https://doi.org/10.1007/s00520-015-2759-9
doi: 10.1007/s00520-015-2759-9
pubmed: 25962615
Kelley AS, Morrison RS (2015) Palliative Care for the Seriously Ill. N Engl J Med 373(8):747–755. https://doi.org/10.1056/NEJMra1404684
doi: 10.1056/NEJMra1404684
pubmed: 26287850
pmcid: 4671283
Wiseman MA (2000) Palliative care dentistry. Gerodontology 17(1):49–51. https://doi.org/10.1111/j.1741-2358.2000.00049.x
doi: 10.1111/j.1741-2358.2000.00049.x
pubmed: 11203514
Henson LA, Maddocks M, Evans C, Davidson M, Hicks S, Higginson IJ (2020Mar 20) Palliative Care and the Management of Common Distressing Symptoms in Advanced Cancer: Pain, Breathlessness, Nausea and Vomiting, and Fatigue. J Clin Oncol 38(9):905–914. https://doi.org/10.1200/JCO.19.00470
doi: 10.1200/JCO.19.00470
pubmed: 32023162
pmcid: 7082153
Soysa NS, Samaranayake LP, Ellepola NA (2004) Cytotoxic drugs, radiotherapy and oral candidiasis. Oral Oncol 40(10):971–978. https://doi.org/10.1016/j.oraloncology.2003.12.013
doi: 10.1016/j.oraloncology.2003.12.013
pubmed: 15509487
Specht L (2002) Oral complications in the head and neck radiation patient. Introduction and scope of the problem. Support Care Cancer 10(1):36–9. https://doi.org/10.1007/s005200100283
doi: 10.1007/s005200100283
pubmed: 11777186
de Oliveira Lula EC, de Oliveira Lula CE, Alves CM, Lopes FF, Pereira AL (2007) Chemotherapy-induced oral complications in leukemic patients. Int J Pediatr Otorhinolaryngol 71(11):1681–1685. https://doi.org/10.1016/j.ijporl.2007.07.006
doi: 10.1016/j.ijporl.2007.07.006
pubmed: 17850887
McCarthy GM, Skillings JR (1992) Orofacial complications of chemotherapy for breast cancer. Oral Surg Oral Med Oral Pathol 74(2):172–178. https://doi.org/10.1016/0030-4220(92)90378-4
doi: 10.1016/0030-4220(92)90378-4
pubmed: 1324459
Siouta N, Beek K, Preston N, Hasselaar J, Hughes S, Payne S et al (2016) Towards integration of palliative care in patients with chronic heart failure and chronic obstructive pulmonary disease: a systematic literature review of European guidelines and pathways. BMC Palliat Care. https://doi.org/10.1186/s12904-016-0089-4
doi: 10.1186/s12904-016-0089-4
pubmed: 27391378
pmcid: 4939056
Provinciali L, Carlini G, Tarquini D et al (2016) Need for palliative care for neurological diseases. Neurol Sci 37(10):1581–1587. https://doi.org/10.1007/s10072-016-2614-x
doi: 10.1007/s10072-016-2614-x
pubmed: 27299428
Pugian Jardim P, Dantas Cavalcanti AC, Santos Borges A, Peclat Flores PV, Achão Rosa C (2022) Signs and symptoms of patients with heart failure in palliative care: scoping review. Anna Nery School Journal of Nursing 26:20220064. https://doi.org/10.1590/2177-9465-EAN-2022-0064en
Voltz R, Borasio G (1997) Palliative therapy in the terminal stage of neurological disease. J Neurol 244(Suppl 4):S2–S10. https://doi.org/10.1007/PL00007721
doi: 10.1007/PL00007721
pubmed: 9402547
Cassolato S, Turnbull R (2003) Xerostomia: clinical aspects and treatment. Gerodontology 20(2):64–77. https://doi.org/10.1111/J.1741-2358.2003.00064.X
doi: 10.1111/J.1741-2358.2003.00064.X
pubmed: 14697016
Connor SR (2020) Global Atlas of Palliative Care, 2nd edn. World Health Organization, London, UK
Chen X, Chen H, Douglas C, Preisser JS, Shuman SK (2013) Dental treatment intensity in frail older adults in the last year of life. J Am Dent Assoc 144(11):1234–1242. https://doi.org/10.14219/jada.archive.2013.0051
doi: 10.14219/jada.archive.2013.0051
pubmed: 24177401
pmcid: 4215005
Vargas J, Hernandez M, Silvestri C, Jiménez O, Guevara N, Carballo M et al (2006) Brain abscess due to Arcanobacterium haemolyticum after dental extraction. Clin Infect Dis 42:1810–1811. https://doi.org/10.1086/504436
doi: 10.1086/504436
pubmed: 16705595
Plemons JM, Al-Hashimi I, Marek CL (2014) American Dental Association Council on Scientific Affairs. Managing xerostomia and salivary gland hypofunction: executive summary of a report from the American Dental Association Council on Scientific Affairs. J Am Dent Assoc 145(8):867–73. https://doi.org/10.14219/jada.2014.44
doi: 10.14219/jada.2014.44
pubmed: 25082939
Phongtankuel V, Meador L, Adelman RD et al (2018) Multicomponent Palliative Care Interventions in Advanced Chronic Diseases: A Systematic Review. Am J Hosp Palliat Med 35(1):173–183. https://doi.org/10.1177/1049909116674669
doi: 10.1177/1049909116674669
Guggenheimer J, Moore PA (2003) Xerostomia: etiology, recognition and treatment. J Am Dent Assoc 134(1):61–69. https://doi.org/10.14219/jada.archive.2003.0018
doi: 10.14219/jada.archive.2003.0018
pubmed: 12555958
Temel JS, Greer JA, Muzikansky A, Gallagher ER, Admane S, Jackson VA, Dahlin CM, Blinderman CD, Jacobsen J, Pirl WF, Billings JA, Lynch TJ (2010) Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med 363:733–742. https://doi.org/10.1056/NEJMoa1000678
doi: 10.1056/NEJMoa1000678
pubmed: 20818875
Lu SY (2021) Oral Candidosis: Pathophysiology and Best Practice for Diagnosis, Classification, and Successful Management. J Fungi (Basel) 7(7):555. https://doi.org/10.3390/jof7070555
doi: 10.3390/jof7070555
pubmed: 34356934
Pedersen AML, Sørensen CE, Proctor GB, Carpenter GH, Ekström J (2018) Salivary secretion in health and disease. J Oral Rehabil 45(9):730–746. https://doi.org/10.1111/joor.12664
doi: 10.1111/joor.12664
pubmed: 29878444
Davies AN (1997) The management of xerostomia: a review. Eur J Cancer Care (Engl) 6(3):209–214. https://doi.org/10.1046/j.1365-2354.1997.00036.x
doi: 10.1046/j.1365-2354.1997.00036.x
pubmed: 9335672
Davies AN, Brailsford SR, Beighton D (2006) Oral candidosis in patients with advanced cancer. Oral Oncol 42(7):698–702. https://doi.org/10.1016/j.oraloncology.2005.11.010
doi: 10.1016/j.oraloncology.2005.11.010
pubmed: 16527512
Douglass AB, Douglass JM (2003) Common dental emergencies. Am Fam Physician 67(3):511–516
pubmed: 12588073
Vissink A, Jansma J, Spijkervet FK, Burlage FR, Coppes RP (2003) Oral sequelae of head and neck radiotherapy. Crit Rev Oral Biol Med 14(3):199–212. https://doi.org/10.1177/154411130301400305
doi: 10.1177/154411130301400305
pubmed: 12799323
Hong CHL, Napeñas JJ, Hodgson BD et al (2010) A systematic review of dental disease in patients undergoing cancer therapy. Support Care Cancer 18(8):1007–1021. https://doi.org/10.1007/s00520-010-0873-2
doi: 10.1007/s00520-010-0873-2
pubmed: 20449756
pmcid: 2914291
Holmstrup P, Plemons J, Meyle J (2018) Non-plaque-induced gingival diseases. J Clin Periodontol 45(Suppl 20):S28–S43. https://doi.org/10.1111/jcpe.12938
doi: 10.1111/jcpe.12938
pubmed: 29926497
Trombelli L, Farina R, Silva CO, Tatakis DN (2018) Plaque-induced gingivitis: Case definition and diagnostic considerations. J Clin Periodontol 45(Suppl 20):S44–S67. https://doi.org/10.1111/jcpe.12939
doi: 10.1111/jcpe.12939
pubmed: 29926492
Navarrete-Reyes AP et al (2023) Oral health in older adults with cancer. Geriatr, Gerontol Aging 17:1–12. https://doi.org/10.53886/gga.e0230016
doi: 10.53886/gga.e0230016