Glycogen synthase kinase 3 inhibition controls

Medical Microbiology Microbiology Molecular biology

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
16 Aug 2024
Historique:
received: 08 02 2024
revised: 20 05 2024
accepted: 17 07 2024
medline: 23 8 2024
pubmed: 23 8 2024
entrez: 23 8 2024
Statut: epublish

Résumé

Compounds targeting host control of infectious diseases provide an attractive alternative to antimicrobials. A phenotypic screen of a kinase library identified compounds targeting glycogen synthase kinase 3 as potent inhibitors of

Identifiants

DOI: 10.1016/j.isci.2024.110555 PMID: 39175770 PMC: PMC11340618
pubmed: 39175770
doi: 10.1016/j.isci.2024.110555
pii: S2589-0042(24)01780-2
pmc: PMC11340618
doi:

Types de publication

Journal Article

Langues

eng

Pagination

110555

Informations de copyright

© 2024 The Author(s).

Déclaration de conflit d'intérêts

S.Pe. is the president, and he and his family are the major shareholders, of Kinexus Bioinformatics Corporation.

Auteurs

Sandra Peña-Díaz (S)

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

Joseph D Chao (JD)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Celine Rens (C)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Hasti Haghdadi (H)

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

Xingji Zheng (X)

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

Keegan Flanagan (K)

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.

Mary Ko (M)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Tirosh Shapira (T)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Adrian Richter (A)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany.

Danay Maestre-Batlle (D)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Julio Ortiz Canseco (JO)

Host-pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, London, UK.

Maximiliano Gabriel Gutierrez (MG)

Host-pathogen Interactions in Tuberculosis Laboratory, The Francis Crick Institute, London, UK.

Khanh Dao Duc (KD)

Department of Mathematics, University of British Columbia, Vancouver, BC, Canada.

Steven Pelech (S)

Department of Medicine, University of British Columbia, Vancouver, BC, Canada.
Kinexus Bioinformatics Corporation, 8755 Ash Street, Vancouver, BC, Canada.

Yossef Av-Gay (Y)

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.
Department of Medicine, University of British Columbia, Vancouver, BC, Canada.

Classifications MeSH