Molecular Dynamics-Ensemble Docking and Biophysical Studies for Structure-Based Identification of Non-Amino Acidic Ligands of DDAH-1.

Journal

Journal of chemical information and modeling
ISSN: 1549-960X
Titre abrégé: J Chem Inf Model
Pays: United States
ID NLM: 101230060

Informations de publication

Date de publication:
23 Aug 2024
Historique:
medline: 23 8 2024
pubmed: 23 8 2024
entrez: 23 8 2024
Statut: aheadofprint

Résumé

Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) accounts for the catabolism of the endogenous inhibitors of nitric oxide (NO) synthases, namely, ADMA (

Identifiants

DOI: 10.1021/acs.jcim.4c01150 PMID: 39177258
pubmed: 39177258
doi: 10.1021/acs.jcim.4c01150
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Carlo Bigiotti (C)

Department of Pharmaceutical Sciences, University of Perugia, via del Liceo 1, 06123 Perugia, Italy.

Elisa Bianconi (E)

Department of Pharmaceutical Sciences, University of Perugia, via del Liceo 1, 06123 Perugia, Italy.

Luana Ruta (L)

Department of Experimental Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy.

Silvia Grottelli (S)

Department of Experimental Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy.

Alice Coletti (A)

Department of Pharmaceutical Sciences, University of Perugia, via del Liceo 1, 06123 Perugia, Italy.

Mirco Dindo (M)

Department of Experimental Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy.

Andrea Carotti (A)

Department of Pharmaceutical Sciences, University of Perugia, via del Liceo 1, 06123 Perugia, Italy.
ORCID: 0000-0001-6097-3996

Barbara Cellini (B)

Department of Experimental Medicine and Surgery, University of Perugia, P.le Gambuli, 06132 Perugia, Italy.
ORCID: 0000-0002-5221-9288

Antonio Macchiarulo (A)

Department of Pharmaceutical Sciences, University of Perugia, via del Liceo 1, 06123 Perugia, Italy.
ORCID: 0000-0001-9535-4183

Classifications MeSH