Prevalence of nonalcoholic fatty liver disease in Pakistan: a systematic review and meta-analysis.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
23 Aug 2024
Historique:
received: 26 05 2024
accepted: 16 08 2024
medline: 24 8 2024
pubmed: 24 8 2024
entrez: 23 8 2024
Statut: epublish

Résumé

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition globally and the leading cause of liver-related death and morbidity. The goal of this study was to collect current data in order to calculate the pooled prevalence of NAFLD in Pakistan. We conducted a comprehensive literature search on four electronic databases until March 2024 to find studies on the prevalence of NAFLD in Pakistan. Pooled prevalence estimates of NAFLD were obtained using random-effects meta-analytic models. The chi-square test was used to account for study heterogeneity, whereas the I

Identifiants

pubmed: 39179792
doi: 10.1038/s41598-024-70481-9
pii: 10.1038/s41598-024-70481-9
doi:

Types de publication

Journal Article Systematic Review Meta-Analysis

Langues

eng

Sous-ensembles de citation

IM

Pagination

19573

Informations de copyright

© 2024. The Author(s).

Références

Cotter, T. G. & Rinella, M. Nonalcoholic fatty liver disease 2020: The state of the disease. Gastroenterology 158(7), 1851–1864 (2020).
pubmed: 32061595 doi: 10.1053/j.gastro.2020.01.052
Roden, M. Mechanisms of disease: Hepatic steatosis in type 2 diabetes—Pathogenesis and clinical relevance. Nat. Clin. Pract. Endocrinol. Metab. 2(6), 335–348 (2006).
pubmed: 16932311 doi: 10.1038/ncpendmet0190
Pafili, K., Maltezos, E. & Papanas, N. Ipragliflozin and sodium glucose transporter 2 inhibitors to reduce liver fat: will the prize we sought be won?. Expert Opin. Pharmacother. 19(3), 185–187 (2018).
pubmed: 29202593 doi: 10.1080/14656566.2017.1413346
Zaharia, O. P. et al. Risk of diabetes-associated diseases in subgroups of patients with recent-onset diabetes: A 5-year follow-up study. Lancet Diabetes Endocrinol. 7(9), 684–694 (2019).
pubmed: 31345776 doi: 10.1016/S2213-8587(19)30187-1
Anstee, Q. M., Targher, G. & Day, C. P. Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis. Nat. Rev. Gastroenterol. Hepatol. 10(6), 330–344 (2013).
pubmed: 23507799 doi: 10.1038/nrgastro.2013.41
Targher, G., Lonardo, A. & Byrne, C. D. Nonalcoholic fatty liver disease and chronic vascular complications of diabetes mellitus. Nat. Rev. Endocrinol. 14(2), 99–114 (2018).
pubmed: 29286050 doi: 10.1038/nrendo.2017.173
Browning, J. D. et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology 40, 1387–1395 (2004).
pubmed: 15565570 doi: 10.1002/hep.20466
Blachier, M., Leleu, H., Peck-Radosavljevic, M., Valla, D. C. & Roudot-Thoraval, F. The burden of liver disease in Europe: A review of available epidemiological data. J. Hepatol. 58, 593–608 (2013).
pubmed: 23419824 doi: 10.1016/j.jhep.2012.12.005
Wong, S. W. & Chan, W. K. Epidemiology of nonalcoholic fatty liver disease in Asia. Indian J. Gastroenterol. 39, 1–8 (2020).
pubmed: 32152903 doi: 10.1007/s12664-020-01018-x
Singh, S., Kuftinec, G. N. & Sarkar, S. Nonalcoholic fatty liver disease in South Asians: A review of the literature. J. Clin. Transl. Hepatol. 5(1), 76 (2017).
pubmed: 28507930 pmcid: 5411360
Pellicano, R. & Fagoonee, S. Nonalcoholic fatty liver disease in South India. J. Postgrad. Med. 57(3), 257 (2011).
pubmed: 21941075 doi: 10.4103/0022-3859.85227
Bhupathiraju, S. N. & Hu, F. B. Epidemiology of obesity and diabetes and their cardiovascular complications. Circ. Res. 118(11), 1723–1735 (2016).
pubmed: 27230638 pmcid: 4887150 doi: 10.1161/CIRCRESAHA.115.306825
Akhtar, S., Nasir, J. A., Abbas, T. & Sarwar, A. Diabetes in Pakistan: A systematic review and meta-analysis. Pak. J. Med. Sci. 35(4), 1173 (2019).
pubmed: 31372163 pmcid: 6659044 doi: 10.12669/pjms.35.4.194
Basit, A., Fawwad, A., Qureshi, H. & Shera, A. S. Prevalence of diabetes, pre-diabetes and associated risk factors: second national diabetes survey of Pakistan (NDSP), 2016–2017. BMJ Open 8(8), e020961 (2018).
pubmed: 30082350 pmcid: 6078264 doi: 10.1136/bmjopen-2017-020961
Akhtar, S., Khan, Z., Rafiq, M. & Khan, A. Prevalence of type II diabetes in district dir lower in Pakistan. Pak. J. Med. Sci. 32(3), 622 (2016).
pubmed: 27375702 pmcid: 4928411 doi: 10.12669/pjms.323.9795
Akhtar, S., Javed, S. & Alina, A. Prevalence of diabetes and prediabetes in district Swat Pakistan. JPMA. J. Pak. Med. Assoc. 71, 243–246 (2021).
pubmed: 35157657
Adil, S. O., Islam, M. A., Musa, K. I. & Shafique, K. Prevalence of metabolic syndrome among apparently healthy adult population in Pakistan: A systematic review and meta-analysis. Healthcare 11, 531 (2023).
pubmed: 36833064 pmcid: 9957355 doi: 10.3390/healthcare11040531
Tanzil, S. & Jamali, T. Obesity, an emerging epidemic in Pakistan a review of evidence. J. Ayub Med. Coll. Abbottabad 28(3), 597–600 (2016).
pubmed: 28712244
Page, M. J. et al. The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. Int. J. Surg. 88, 105906 (2021).
pubmed: 33789826 doi: 10.1016/j.ijsu.2021.105906
Freeman, M. F. & Tukey, J. O. W. Transformations related to the angular and the square root. Ann. Math. Stat. 21, 607–611 (1950).
doi: 10.1214/aoms/1177729756
Higgins, J. P. T. & Thompson, S. G. Quantifying heterogeneity in a meta-analysis. Stat. Med. 21(11), 1539–1558 (2002).
pubmed: 12111919 doi: 10.1002/sim.1186
Begg, C. B. & Mazumdar, M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1, 1088–1101 (1994).
doi: 10.2307/2533446
Egger, M., Smith, G. D., Schneider, M. & Minder, C. Bias in meta-analysis detected by a simple, graphical. BMJ 316, 469 (1998).
doi: 10.1136/bmj.316.7129.469
Wallace, B. C. et al. Meta-analyst: Software for meta-analysis of binary, continuous and diagnostic data. BMC Med. Res. Methodol. 9, 80. https://doi.org/10.1186/1471-2288-9-80 (2009).
doi: 10.1186/1471-2288-9-80 pubmed: 19961608 pmcid: 2795760
Viera, A. J. & Garrett, J. M. Understanding interobserver agreement: The kappa statistic. Fam. Med. 37, 360–363 (2005).
pubmed: 15883903
Khan, S. M. et al. Prevalence of ultrasound diagnosed fatty liver disease in adult patient in a hospital in North West of Pakistan: A community-based study. Med. Forum 33, 11 (2022).
Iqbal, S., Khan, S., Iqbal, M. D. & Iman, N. U. Frequency of nonalcoholic fatty liver disease in general medical out patients. J. Med. Sci. 26(3), 202–206 (2018).
Shah, A. S., Khan, S. R., Chishti, K. A. & Khan, A. G. Prevalence of non alcoholic fatty liver and non alcoholic steatohepatitis in peshawar cantonment, Khyber Pakhtunkhwa Pakistan. Pak. J. Pharm. Sci. 31(1), 193–199 (2018).
pubmed: 29348103
Kanwal, S., Ghaffar, T., Aamir, A. H. & Usman, K. Frequency of non-alcoholic fatty liver disease in patients with type-2 diabetes mellitus and its associated risk factors. Pak. J. Med. Sci. 37(5), 1335 (2021).
pubmed: 34475908 pmcid: 8377887 doi: 10.12669/pjms.37.5.4211
Ullah, S. et al. Risk factor analysis and prevalence of the non-alcoholic fatty liver disease in patients with type-ii diabetes mellitus. Pak. J. Med. Health Sci. 16(04), 557–557 (2022).
doi: 10.53350/pjmhs22164557
Umair, M., et al. Frequency of non-alcoholic fatty liver disease in non-obese type 2 diabetic patients and its association with sex and age. Adv. Basic Med. Sci. 3(1), (2019).
Fatima, M. et al. Prevalence and identification of fatty liver (FL) risk markers in local Pakistani population. J. Chem. Pharm. Res. 7(10), 23–29 (2015).
Alavi, N., Amin, S. & Mumtaz, M. Non-alcoholic fatty liver disease (NAFLD): Frequency in diabetes mellitus (type ii) patients and non diabetic group at shalamar medical and dental college Lahore. Prof. Med. J. 23(01), 029–033 (2016).
Rashid, A., Zafar, S., Bashir, A., Bakht, K. & Bhalli, A. U. Presence of non-alcoholic fatty liver disease in patients of uncontrolled and controlled type 2 diabetes mellitus. Pak. Armed Forces Med. J. 69(4), 822–825 (2019).
Ijaz-ul-Haque Taseer, L. H., Safdar, S., Mirbahar, A. M. & Ahmad, I. Frequency of non alcoholic fatty liver disease (NAFLD) and its biochemical derangements in type-2 diabetic patients. Pak. J. Med. Sci. 25(5), 817–820 (2009).
Afzal, M. Y., Anjum, H. S., Siddiqui, U. N. & Shaihd, S. Nonalcoholic fatty liver disease (NAFLD) frequency in diabetes mellitus (DM) type–II patients. FUUAST J. Biol. 6(1), 7–10 (2016).
Iftikhar, R., Kamran, S. M., Sher, F. & Wahla, M. S. Prevalence of nonalcoholic fatty liver disease in patients with metabolic syndrome: Non-alcoholic fatty liver disease. Pak. Armed Forces Med. J. 65(5), 616–619 (2015).
Shah, S. U. et al. Association of type 2 diabetes mellitus with fatty liver. Pak. Armed Forces Med. J. 72(6), 2018–2020 (2022).
doi: 10.51253/pafmj.v72i6.4551
Adnan, M. et al. Sociodemographic and genetic determinants of nonalcoholic fatty liver disease in type 2 diabetes mellitus patients. J. Genet. Eng. Biotechnol. 20, 68 (2022).
pubmed: 35486295 pmcid: 9054952 doi: 10.1186/s43141-022-00349-w
Ali, A. et al. Frequency of non-alcoholic fatty liver disease (NAFLD) and its associated risk factors among Type-2 diabetics. Pak. J. Med. Sci. 38(1), 28 (2022).
pubmed: 35035396 pmcid: 8713246
Ismail, A. & Anjum, J. Nonalcoholic fatty liver diseases in newly analyzed diabetes mellitus patients with risk factors. Pak. J. Med. Health Sci. 16(04), 570–570 (2022).
doi: 10.53350/pjmhs22164570
Rasheed, A., Butt, N. I., Yasin, F. Aslam, H., Shahid, K., Kanwal, N. Frequencies of Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome in Lean Individuals. (2023).
Waseem, M., Saeed, F. & Khan, R. Ultrasound detected non-alcoholic fatty liver disease prevalence and its risk factors in Pakistani population. Adv. Life Sci. 9(4), 607–611 (2023).
Aziz, B., Nazar, T. & Irfan, M. The frequency of non-alcoholic fatty liver disease in non-obese young medical professionals. JPMA 71(7), 1878–1881 (2021).
Ansari, A. M. et al. Risk factors for non-alcoholic fatty liver disease: a cross-sectional study in Pakistani population. KJMS 13(2), 287 (2020).
Bano, U., Gondal, M., Moin, S. Evaluation of risk factors of non alcoholic fatty liver disease (NAFLD) in a tertiary care hospital at Rawalpindi, Pakistan: a local experience. J. Postgrad. Med. Inst., 22(3), (2008).
Naveed, S. et al. Type 2 diabetes: Non alcoholic fatty liver disease (NAFLD). Prof. Med. J. 23(02), 138–146 (2016).
Luxmi, S., Sattar, R. A. & Ara, J. Association of non-alcoholic fatty liver with type 2 diabetes mellitus. JLUMHS 9, 188–193 (2008).
Butt, A. S. et al. Nonalcoholic fatty liver diseases among recently diagnosed patients with diabetes mellitus and risk factors. Euroasian J. Hepato Gastroenterol. 9(1), 9 (2019).
doi: 10.5005/jp-journals-10018-1288
Jabeen, R., Mobin, A., Mehmood, K. & Ali, S. T. Frequency of pre-diabetes, diabetes mellitus in non-alcoholic fatty liver disease. Prof. Med. J. 27(08), 1703–1709 (2020).
Butt, A. S. et al. S1166 prevalence and the risk factors of nonalcoholic fatty liver disease in urban population of Karachi, Pakistan: A community-based study. Am. Coll. Gastroenterol. 115, 5831 (2020).
Latif, A., Jaffar, S. R., Saleem, M. Validation of fatty liver index for nonalcoholic fatty liver disease in Pakistani adults. Pak. J. Pathol. 28(1), (2017).
Abbas, Z. et al. Non-alcoholic fatty liver disease among visitors to a hepatitis awareness programme. Trop. Gastroenterol. 34(3), 153–158 (2014).
doi: 10.7869/tg.119
Niaz, A., Ali, Z., Nayyar, S. & Fatima, N. Prevalence of NAFLD in healthy and young male individuals. Int. Sch. Res. Notices 2011, 1–4 (2011).
Shaikh, F., Qarni, A., Fatima, K. & Aziz, S. The liver associated diseases in patient with diabetes mellitus from Islamabad region. J. Bashir Inst. Health Sci. 4(2), 146–152 (2023).
Khan, R. et al. Frequency of non-alcoholic fatty liver disease among the non-obese population presenting to the gastrointestinal outpatient clinic. J. Liaquat. Natl. Hosp. 1, 117–121 (2024).
Jafar, Z. S., Ahmed, A., Akram, M. N., Mirza, M. J. & Ahtesham, K. Frequency of non-alcoholic fatty liver disease (NAFLD) and its association with diabetes mellitus, hypertension and cholelithiasis among patients undergoing routine ultrasonography. JAIMC 20, 100–104 (2022).
Nawab, A., et al. Frequency of non-alcoholic fatty liver disease in type 2 diabetes mellitus. J. Pharm. Negative Res. 3962–3967. (2023).
Yousafzai, R. A. et al. Frequency of non-alcoholic fatty liver disease in adults with diabetes mellitus. Pak. Armed Forces Med. J. 73(4), 993–995 (2023).
doi: 10.51253/pafmj.v73i4.3538
Niriella, M. A. et al. Prevalence and associated factors for non-alcoholic fatty liver disease among adults in the South Asian Region: A meta-analysis. Lancet Reg. Health South. Asia 1, 15 (2023).
Teng, M. L. et al. Global incidence and prevalence of nonalcoholic fatty liver disease. Clin. Mol. Hepatol. 29, 32 (2023).
doi: 10.3350/cmh.2022.0365
Sinha, A. & Bankura, B. Prevalence of nonalcoholic fatty liver disease in type 2 diabetes mellitus patients from the Eastern region of India. Diabetes Epidemiol. Manag. 7, 100161 (2023).
doi: 10.1016/j.deman.2023.100161
Bhatt, H. B. & Smith, R. J. Fatty liver disease in diabetes mellitus. Hepatobiliary Surg. Nutr. 4(2), 101 (2015).
pubmed: 26005676 pmcid: 4405411
Mata, D. A. et al. Prevalence of depression and depressive symptoms among resident physicians. JAMA 314(22), 2373 (2015).
pubmed: 26647259 pmcid: 4866499 doi: 10.1001/jama.2015.15845

Auteurs

Fazal Hassan (F)

Department of Mathematics and Statistics, The University of Haripur, Haripur, KP, Pakistan.

Maria Farman (M)

Department of Statistics, GCU, Lahore, Pakistan.

Kauser Aftab Khan (KA)

Department of Community Medicine Gujranwala, Medical College Gujranwala, Gujranwala, Pakistan.

Muhammad Awais (M)

Department of Statistics, GCU, Lahore, Pakistan.

Sohail Akhtar (S)

Department of Mathematics and Statistics, The University of Haripur, Haripur, KP, Pakistan. s.akhtar@uoh.edu.pk.

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